Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
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Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkBBrain-derived neurotrophic factor-tropomyosin-related kinase B signaling contributes to activity-dependent changes in synaptic proteinsHarnessing the power of metabolism for seizure prevention: focus on dietary treatmentsAblation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal deathA Jacob/Nsmf Gene Knockout Results in Hippocampal Dysplasia and Impaired BDNF Signaling in Dendritogenesis.Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon VectorsTrkb signaling in pericytes is required for cardiac microvessel stabilizationAdult Deletion of SRF Increases Epileptogenesis and Decreases Activity-Induced Gene Expression.2-Deoxy-D-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structureCyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in miceN-methyl-D-aspartic acid receptor activation downregulates expression of δ subunit-containing GABAA receptors in cultured hippocampal neurons.ERK activation causes epilepsy by stimulating NMDA receptor activityLoss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis.Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy.Decreased CREB levels suppress epilepsyThe paraventricular thalamus controls a central amygdala fear circuit.Exercise-induced motor improvement after complete spinal cord transection and its relation to expression of brain-derived neurotrophic factor and presynaptic markers.Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF.Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathwaysMutual regulation of Src family kinases and the neurotrophin receptor TrkB.Impairment of kindling development in phospholipase Cγ1 heterozygous mice.Disruption of TrkB-mediated phospholipase Cgamma signaling inhibits limbic epileptogenesisBrain-derived neurotrophic factor and epilepsy--a missing link?Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticusAnticonvulsant and antiepileptic actions of 2-deoxy-D-glucose in epilepsy modelsNeurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome.Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF).Localization of brain-derived neurotrophic factor to distinct terminals of mossy fiber axons implies regulation of both excitation and feedforward inhibition of CA3 pyramidal cellsSmall-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.The BDNF effects on dendritic spines of mature hippocampal neurons depend on neuronal activityNovel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response.Epigenetic gene regulation in the adult mammalian brain: multiple roles in memory formation.Expansion of the dentate mossy fiber-CA3 projection in the brain-derived neurotrophic factor-enriched mouse hippocampus.Candidate drug targets for prevention or modification of epilepsyEstrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of steroid hormone-growth factor interactions in the adult CNS.Disruption of Fgf13 causes synaptic excitatory-inhibitory imbalance and genetic epilepsy and febrile seizures plusChanges in expression of BDNF and its receptors TrkB and p75NTR in the hippocampus of a dog model of chronic alcoholism and abstinence.Reduction of TrkB expression de novo in the adult mouse impairs epileptogenesis in the kindling model.Rapid transient isoform-specific neuregulin1 transcription in motor neurons is regulated by neurotrophic factors and axon-target interactionsTo BDNF or not to BDNF: that is the epileptic hippocampus.
P2860
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P2860
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
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2004年學術文章
@zh-hant
name
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@en
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@nl
type
label
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@en
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@nl
prefLabel
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@en
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@nl
P2093
P1433
P1476
Conditional deletion of TrkB but not BDNF prevents epileptogenesis in the kindling model.
@en
P2093
Bryan W Luikart
James O McNamara
Luis F Parada
Robert Kotloski
Xiao-Ping He
P356
10.1016/J.NEURON.2004.06.019
P407
P577
2004-07-01T00:00:00Z