about
Clinical and serological evaluation of a novel CENP-A peptide based ELISAAutoantibody detection using indirect immunofluorescence on HEp-2 cells.The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosusActive systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation.Humoral immunity and long-lived plasma cells.The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.Certolizumab pegol plus methotrexate provides broad relief from the burden of rheumatoid arthritis: analysis of patient-reported outcomes from the RAPID 2 trialThe role of long-lived plasma cells in autoimmunity.Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study.Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus.Anti-dsDNA-NcX ELISA: dsDNA-loaded nucleosomes improve diagnosis and monitoring of disease activity in systemic lupus erythematosus.γ-Secretase directly sheds the survival receptor BCMA from plasma cellsImpact of switching from mycophenolate mofetil to enteric-coated mycophenolate sodium on gastrointestinal side effects in patients with autoimmune disease: a Phase III, open-label, single-arm, multicenter studyBelimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosusMaintenance of serum antibody levels.Long-lived plasma cells and their contribution to autoimmunity.Analyzing pathogenic (double-stranded (ds) DNA-specific) plasma cells via immunofluorescence microscopy.Developments in lupus 2006Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice.Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray.Adaptation of humoral memory.Competence and competition: the challenge of becoming a long-lived plasma cell.Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases: the evolution from myeloablative to lymphoablative transplant regimens.Plasma cell differentiation and survival.Antibodies against PM/Scl-75 and PM/Scl-100 are independent markers for different subsets of systemic sclerosis patients.Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort.Terminal complement activation is increased and associated with disease severity in CIDPSevere disease activity and complications of immunosuppressive therapy: a challenge for acute hospital-based rehabilitation in rheumatology.Current state and future directions of autologous hematopoietic stem cell transplantation in systemic lupus erythematosus.SIGLEC1 is a biomarker of disease activity and indicates extraglandular manifestation in primary Sjögren's syndrome.The protein tyrosine phosphatase PTP1B is a negative regulator of CD40 and BAFF-R signaling and controls B cell autoimmunity.Biomarkers as tools for improved diagnostic and therapeutic monitoring in systemic lupus erythematosisMemory B and memory plasma cells.Long-lived autoreactive plasma cells drive persistent autoimmune inflammation.Pathogenic long-lived plasma cells and their survival niches in autoimmunity, malignancy, and allergy.Where is lupus hidden?Repeated administration of dapirolizumab pegol in a randomised phase I study is well tolerated and accompanied by improvements in several composite measures of systemic lupus erythematosus disease activity and changes in whole blood transcriptomic pPlasma cells as an innovative target in autoimmune disease with renal manifestations.Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic options.
P50
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P50
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Falk Hiepe
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Falk Hiepe
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Falk Hiepe
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Falk Hiepe
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Falk Hiepe
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