Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
about
Genome Editing Tools in Plants.The Future of Multiplexed Eukaryotic Genome Engineering.Enhancing the RNA engineering toolkit.Harnessing natural DNA modifying activities for editing of the genome and epigenome.Racing for academic glory and patents: Lessons from CRISPR.Rewritable multi-event analog recording in bacterial and mammalian cells.Commentary: Programmable base editing of A·T to G·C in genomic DNA without DNA cleavage.Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.New tools for old drugs: Functional genetic screens to optimize current chemotherapy.Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.Programmable Single and Multiplex Base-Editing in Bombyx mori Using RNA-Guided Cytidine Deaminases.Engineering the Drosophila Genome for Developmental Biology.Homology-Directed Repair of a Defective Glabrous Gene in Arabidopsis With Cas9-Based Gene Targeting.Diversification of AID/APOBEC-like deaminases in metazoa: multiplicity of clades and widespread roles in immunity.Expanded base editing in rice and wheat using a Cas9-adenosine deaminase fusion.Guiding Lights in Genome Editing for Inherited Retinal Disorders: Implications for Gene and Cell Therapy.Highly efficient base editing in Staphylococcus aureus using an engineered CRISPR RNA-guided cytidine deaminase.Commentary: RNA editing with CRISPR-Cas13.Genome Editing Redefines Precision Medicine in the Cardiovascular Field.In vivo base editing of post-mitotic sensory cells.CRISPR base editors: genome editing without double-stranded breaks.Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.The CRISPR tool kit for genome editing and beyond.In Vivo Applications of CRISPR-Based Genome Editing in the Retina.Exploration of genetic basis underlying individual differences in radiosensitivity within human populations using genome editing technology.Optimizing CRISPR/Cas9 for the Diatom Phaeodactylum tricornutum.The Current State of Cephalopod Science and Perspectives on the Most Critical Challenges Ahead From Three Early-Career Researchers.Zebrafish Models of Rare Hereditary Pediatric Diseases.Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 with improved proof-reading enhances homology-directed repair.Highly efficient RNA-guided base editing in rabbit.Delivering CRISPR: a review of the challenges and approachesContinuous directed evolution of proteins with improved soluble expressionProtein Engineering Strategies to Expand CRISPR-Cas9 ApplicationsDouble Selection Enhances the Efficiency of Target-AID and Cas9-Based Genome Editing in YeastHighly efficient base editing in bacteria using a Cas9-cytidine deaminase fusionEx Vivo COL7A1 Correction for Recessive Dystrophic Epidermolysis Bullosa Using CRISPR/Cas9 and Homology-Directed RepairThe classification, genetic diagnosis and modelling of monogenic autoinflammatory disordersThe Current State and Future of CRISPR-Cas9 gRNA Design ToolsCRISPR/Cascade 9-Mediated Genome Editing-Challenges and OpportunitiesCRISPR-Cas9/Cas12a biotechnology and application in bacteria
P2860
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P2860
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh-hant
name
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@en
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@nl
type
label
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@en
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@nl
prefLabel
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@en
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@nl
P2093
P2860
P356
P1433
P1476
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.
@en
P2093
Ahmed H Badran
Alexis C Komor
David I Bryson
David R Liu
Holly A Rees
Michael S Packer
Nicole M Gaudelli
P2507
P2860
P2888
P304
P356
10.1038/NATURE24644
P407
P577
2017-10-25T00:00:00Z
P6179
1092351376