Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells.
about
Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatmentCholine Metabolism Alteration: A Focus on Ovarian CancerCholine metabolism-based molecular diagnosis of cancer: an updatePhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsPhosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell ModelInhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells.Phosphatidylcholine-specific phospholipase C inhibition down- regulates CXCR4 expression and interferes with proliferation, invasion and glycolysis in glioma cells.Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models.The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy.Inhibition of phosphatidylcholine-specific phospholipase C results in loss of mesenchymal traits in metastatic breast cancer cells.Nuclear phosphoinositide-specific phospholipase C β1 controls cytoplasmic CCL2 mRNA levels in HIV-1 gp120-stimulated primary human macrophages.Targeting annexin A7 by a small molecule suppressed the activity of phosphatidylcholine-specific phospholipase C in vascular endothelial cells and inhibited atherosclerosis in apolipoprotein E⁻/⁻miceCholine metabolism in malignant transformation.Inhibition of Phosphatidylcholine-Specific Phospholipase C Interferes with Proliferation and Survival of Tumor Initiating Cells in Squamous Cell CarcinomaGlobal metabolic profile identifies choline kinase alpha as a key regulator of glutathione-dependent antioxidant cell defense in ovarian carcinomaIn vivo detection of phospholipase C by enzyme-activated near-infrared probes.A quantitative continuous enzyme assay of intramolecularly quenched fluorogenic phospholipase substrates for molecular imaging.Synthesis and Evaluation of Cytosolic Phospholipase A(2) Activatable Fluorophores for Cancer Imaging.Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma.Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer.Monitoring response to cytostatic cisplatin in a HER2(+) ovary cancer model by MRI and in vitro and in vivo MR spectroscopy.MR evaluation of response to targeted treatment in cancer cells.Tricyclodecan-9-yl-xanthogenate (D609) mechanism of actions: a mini-review of literature.Targeting Phospholipid Metabolism in Cancer.Characterisation of in vivo ovarian cancer models by quantitative 1H magnetic resonance spectroscopy and diffusion-weighted imaging.Human prostate cell lines from normal and tumourigenic epithelia differ in the pattern and control of choline lipid headgroups released into the medium on stimulation of protein kinase C.Nuclear magnetic resonance detects phosphoinositide 3-kinase/Akt-independent traits common to pluripotent murine embryonic stem cells and their malignant counterparts.Design and synthesis of phospholipase C and A2-activatable near-infrared fluorescent smart probes.Activation of Phosphatidylcholine-Specific Phospholipase C in Breast and Ovarian Cancer: Impact on MRS-Detected Choline Metabolic Profile and Perspectives for Targeted TherapyPhosphatidylcholine-specific phospholipase C inhibition reduces HER2-overexpression, cell proliferation and in vivo tumor growth in a highly tumorigenic ovarian cancer model.Core-based lipid nanoparticles as a nanoplatform for delivery of near-infrared fluorescent imaging agents.Inhibitory effect of chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells.Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells.Regulation of neural progenitor cell proliferation by D609: potential role for ERK.Lipopolysaccharide activated phosphatidylcholine-specific phospholipase C and induced IL-8 and MCP-1 production in vascular endothelial cells.Phosphatidylethanolamine binding protein 1 in vacular endothelial cell autophagy and atherosclerosis.
P2860
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P2860
Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@en
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@nl
type
label
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@en
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@nl
prefLabel
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@en
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@nl
P2093
P50
P1433
P1476
Phosphatidylcholine-specific p ...... ithelial ovarian cancer cells.
@en
P2093
Carlo Ramoni
Franca Podo
Paola Alberti
Serena Cecchetti
Silvana Canevari
Silvia Miotti
P304
P356
10.1158/0008-5472.CAN-07-6763
P407
P577
2008-08-01T00:00:00Z