VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.
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Intramuscular viral delivery of paraplegin rescues peripheral axonopathy in a model of hereditary spastic paraplegiaAltering the tropism of lentiviral vectors through pseudotyping.Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosisNeuroprotection as a Therapeutic Target for Diabetic RetinopathyTrophic factors as modulators of motor neuron physiology and survival: implications for ALS therapyCMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.Non-Viral Nucleic Acid Delivery Strategies to the Central Nervous SystemCo-induction of the heat shock response ameliorates disease progression in a mouse model of human spinal and bulbar muscular atrophy: implications for therapyALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseMetformin treatment has no beneficial effect in a dose-response survival study in the SOD1(G93A) mouse model of ALS and is harmful in female miceExendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosisRoles of the endogenous VEGF receptors flt-1 and flk-1 in astroglial and vascular remodeling after brain injuryKCTD20, a relative of BTBD10, is a positive regulator of AktThe related transcriptional enhancer factor-1 isoform, TEAD4(216), can repress vascular endothelial growth factor expression in mammalian cellsThe expression of VEGF-A is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosisNeurovascular pathways to neurodegeneration in Alzheimer's disease and other disordersFlt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo.Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons.Specific retrograde transduction of spinal motor neurons using lentiviral vectors targeted to presynaptic NMJ receptorsExtensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord.Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptorsDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis.Human nerual stem cells for brain repairRoles of vascular endothelial growth factor in amyotrophic lateral sclerosis.Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis miceOptical control of retrogradely infected neurons using drug-regulated "TLoop" lentiviral vectors.Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons.Nerve injection of viral vectors efficiently transfers transgenes into motor neurons and delivers RNAi therapy against ALS.Dose-dependent neuroprotection of VEGF₁₆₅ in Huntington's disease striatumVascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration.Spinal but not cortical microglia acquire an atypical phenotype with high VEGF, galectin-3 and osteopontin, and blunted inflammatory responses in ALS rats.Animal models of Kennedy disease.Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophyComplex genetics of amyotrophic lateral sclerosis.One universal common endpoint in mouse models of amyotrophic lateral sclerosis.Moderate exercise delays the motor performance decline in a transgenic model of ALS.Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?HSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathyAmyotrophic lateral sclerosis: a focus on disease progression
P2860
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P2860
VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@en
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@nl
type
label
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@en
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@nl
prefLabel
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@en
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@nl
P2093
P356
P1433
P1476
VEGF delivery with retrogradel ...... survival in a mouse ALS model.
@en
P2093
Erik Storkebaum
G Scott Ralph
Kyriacos A Mitrophanous
Lucy E Walmsley
Nicholas D Mazarakis
Susan M Kingsman
P2888
P304
P356
10.1038/NATURE02544
P407
P577
2004-05-01T00:00:00Z
P6179
1027983584