about
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formationMechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell linesThe role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damageAnalysis of gene expression using gene sets discriminates cancer patients with and without late radiation toxicityThe UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions.Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.Mechanism and timing of mitotic rearrangements in the subtelomeric D4Z4 repeat involved in facioscapulohumeral muscular dystrophy.Gene and sequence specificity of DNA damage induction and repair: consequences for mutagenesis.PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients.The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding.Deciphering the RNA landscape by RNAome sequencing.Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment.Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation.The gene encoding hypoxanthine-guanine phosphoribosyltransferase as target for mutational analysis: PCR cloning and sequencing of the cDNA from the rat.Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status.Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.An efficient pipeline for the generation and functional analysis of human BRCA2 variants of uncertain significance.Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.Xenobiotic metabolism in differentiated human bronchial epithelial cells.Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells.Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra.Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination.Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers.(6-4) photoproducts and not cyclobutane pyrimidine dimers are the main UV-induced mutagenic lesions in Chinese hamster cells.Strand-specific mutation spectra in repair-proficient and repair-deficient hamster cells.Adverse outcome pathways: opportunities, limitations and open questionsReduced activity of double-strand break repair genes in prostate cancer patients with late normal tissue radiation toxicity.Gene transcription increases DNA damage-induced mutagenesis in mammalian stem cells.Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.Heterozygous Aprt mouse model: detection and study of a broad range of autosomal somatic mutations in vivo.Enhanced global genome nucleotide excision repair reduces UV carcinogenesis and nullifies strand bias in p53 mutations in Csb-/- mice.No threshold for the induction of chromosomal damage at clinically relevant low doses of X rays.Enhanced hprt mutant frequency but no significant difference in mutation spectrum between a smoking and a non-smoking human population.Frequent homologous recombination deficiency in high-grade endometrial carcinomasMolecular analysis of mutations affecting hprt mRNA splicing in human T-lymphocytes in vivoMolecular analysis of mutations induced by N-ethyl-N-nitrosourea at the HPRT locus in mouse lymphoma cells
P50
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P50
description
hulumtues
@sq
researcher
@en
ricercatore
@it
wetenschapper
@nl
հետազոտող
@hy
name
Harry Vrieling
@ast
Harry Vrieling
@en
Harry Vrieling
@es
Harry Vrieling
@nl
Harry Vrieling
@sl
type
label
Harry Vrieling
@ast
Harry Vrieling
@en
Harry Vrieling
@es
Harry Vrieling
@nl
Harry Vrieling
@sl
prefLabel
Harry Vrieling
@ast
Harry Vrieling
@en
Harry Vrieling
@es
Harry Vrieling
@nl
Harry Vrieling
@sl
P1006
P214
P1006
P106
P21
P214
P31
P496
0000-0002-3034-2664
P735
P7859
viaf-287700033