about
The COMBREX project: design, methodology, and initial results.Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilumStructure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643Integrating Structure, Bioinformatics, and Enzymology to Discover Function: BioH, A NEW CARBOXYLESTERASE FROM ESCHERICHIA COLIADP-dependent 6-Phosphofructokinase from Pyrococcus horikoshii OT3: STRUCTURE DETERMINATION AND BIOCHEMICAL CHARACTERIZATION OF PH1645In situ proteolysis for protein crystallization and structure determinationBiochemical and Structural Characterization of a Novel Family of Cystathionine β-Synthase Domain Proteins Fused to a Zn Ribbon-Like DomainStructural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5'-deoxyribonucleotidase YfbR from Escherichia coli.A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeatsFunctional and Structural Characterization of DR_0079 from Deinococcus radiodurans , a Novel Nudix Hydrolase with a Preference for Cytosine (Deoxy)ribonucleoside 5′-Di- and Triphosphates †Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteriaCrystal structure of human retinoblastoma binding protein 9Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coliStructural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain PhosphodiesterasesRiboneogenesis in YeastA dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repairMapping the Reaction Coordinates of Enzymatic DefluorinationAn Inserted α/β Subdomain Shapes the Catalytic Pocket of Lactobacillus johnsonii Cinnamoyl EsteraseBiochemical and Structural Studies of Uncharacterized Protein PA0743 from Pseudomonas aeruginosa Revealed NAD+-dependent L-Serine DehydrogenaseStructure and activity of the Pseudomonas aeruginosa hotdog-fold thioesterases PA5202 and PA2801Structure and activity of the cold-active and anion-activated carboxyl esterase OLEI01171 from the oil-degrading marine bacterium Oleispira antarcticaGenome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarcticaToroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricusBiochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified NucleotidesStructure-Based Mutational Studies of Substrate Inhibition of Betaine Aldehyde Dehydrogenase BetB from Staphylococcus aureusPressure adaptation is linked to thermal adaptation in salt-saturated marine habitatsA family of metal-dependent phosphatases implicated in metabolite damage-controlNucleotide degradation and ribose salvage in yeast.The HD domain of the Escherichia coli tRNA nucleotidyltransferase has 2',3'-cyclic phosphodiesterase, 2'-nucleotidase, and phosphatase activitiesBiochemical diversity of carboxyl esterases and lipases from Lake Arreo (Spain): a metagenomic approachEvolution and classification of the CRISPR-Cas systemsDiversity of hydrolases from hydrothermal vent sediments of the Levante Bay, Vulcano Island (Aeolian archipelago) identified by activity-based metagenomics and biochemical characterization of new esterases and an arabinopyranosidaseMass spectrometry following mild enzymatic digestion reveals phosphorylation of recombinant proteins in Escherichia coli through mechanisms involving direct nucleotide binding.An updated evolutionary classification of CRISPR-Cas systems.The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity.Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.CRISPR RNA binding and DNA target recognition by purified Cascade complexes from Escherichia coliRole of the Streptococcus mutans CRISPR-Cas systems in immunity and cell physiology.
P50
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P50
description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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name
Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexandre Iakounine
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Alexander F. Yakunin
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Alexander F. Yakunin
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Alexander F. Yakunin
@es
Alexander F. Yakunin
@nl
Alexander F. Yakunin
@sl
P106
P1153
7005878575
P21
P31
P496
0000-0003-0813-6490