about
Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysisVascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-DThe Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicityChronic stress in mice remodels lymph vasculature to promote tumour cell dissemination.Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimersVEGF-D promotes the metastatic spread of tumor cells via the lymphaticsVEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenovirusesThe specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and manVascular endothelial growth factor D is dispensable for development of the lymphatic system.Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivoSox18 induces development of the lymphatic vasculature in miceRyk, a receptor regulating Wnt5a-mediated neurogenesis and axon morphogenesis of ventral midbrain dopaminergic neuronsThe Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosumWnt5a regulates midbrain dopaminergic axon growth and guidanceLymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches.Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.The vascular endothelial growth factor family: signalling for vascular development.Vascular endothelial growth factor-D over-expressing tumor cells induce differential effects on uterine vasculature in a mouse model of endometrial cancerTransfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and functionLymphatic vessels in cancer metastasis: bridging the gaps.A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma.The role of tumor lymphangiogenesis in metastatic spread.Lymphangiogenesis and cancer metastasis.A fully human inhibitory monoclonal antibody to the Wnt receptor RYKVascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1Lymphangiogenic growth factor responsiveness is modulated by postnatal lymphatic vessel maturation.Molecular targeting of lymphatics for therapy.Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis.Molecular regulation of the VEGF family -- inducers of angiogenesis and lymphangiogenesis.The prognostic value of immunoperoxidase staining with monoclonal antibodies NCRC-11 and 3E1.2 in breast cancer.Focus on lymphangiogenesis in tumor metastasis.The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling.ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18)A Three-Dimensional Lymphatic Endothelial Cell Tube Formation Assay to Identify Novel Kinases Involved in Lymphatic Vessel Remodeling.Systematic high-content genome-wide RNAi screens of endothelial cell migration and morphology.Lymphatic endothelium: an important interactive surface for malignant cells.The connection between lymphangiogenic signalling and prostaglandin biology: a missing link in the metastatic pathway.Tumor lymphangiogenesis and metastatic spread-new players begin to emerge.Current strategies for modulating lymphangiogenesis signalling pathways in human disease.
P50
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P50
description
hulumtues
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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Steven A Stacker
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P1006
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nb2009026541
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0000-0003-4096-9273
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lccn-nb2009026541