about
Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.Attenuation of miR-126 activity expands HSC in vivo without exhaustion.Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitorsA double-switch vector system positively regulates transgene expression by endogenous microRNA expression (miR-ON vector).Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models.Stable knockdown of microRNA in vivo by lentiviral vectors.A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors.miRNA-126 Orchestrates an Oncogenic Program in B Cell Precursor Acute Lymphoblastic Leukemia.Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy.Mbd3/NuRD controls lymphoid cell fate and inhibits tumorigenesis by repressing a B cell transcriptional program.Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors.Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing
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description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alice Giustacchini
@ast
Alice Giustacchini
@en
Alice Giustacchini
@es
Alice Giustacchini
@nl
Alice Giustacchini
@sl
type
label
Alice Giustacchini
@ast
Alice Giustacchini
@en
Alice Giustacchini
@es
Alice Giustacchini
@nl
Alice Giustacchini
@sl
prefLabel
Alice Giustacchini
@ast
Alice Giustacchini
@en
Alice Giustacchini
@es
Alice Giustacchini
@nl
Alice Giustacchini
@sl
P1053
D-4074-2018
P106
P21
P31
P3829
P496
0000-0002-8733-8594