about
sameAs
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosisCorrelating chemical sensitivity and basal gene expression reveals mechanism of action.Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset.Validation and development of MTH1 inhibitors for treatment of cancer.Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality.Discovery of a Small-Molecule Probe for V-ATPase FunctionEarly Perspective.Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery.DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets.A general enantioselective route to the chamigrene natural product family.NAMPT is the cellular target of STF-31-like small-molecule probes.Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.In Situ Target Engagement Studies in Adherent Cells.Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors.Reprint of: A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growthEnantioselective synthesis of anti-β-hydroxy-α-amido esters by asymmetric transfer hydrogenation in emulsionsDomino carbopalladation-cross-coupling for the synthesis of 3,3-disubstituted oxindolesDomino carbopalladation-carbonylation: generating quaternary stereocenters while controlling beta-hydride eliminationEnantioselective synthesis of anti-β-hydroxy-α-amido esters via transfer hydrogenationAsymmetric transfer hydrogenation coupled with dynamic kinetic resolution in water: synthesis of anti-β-hydroxy-α-amino acid derivativesComputational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell LinesUsing High Content Imaging to Quantify Target Engagement in Adherent CellsPerspective on CETSA Literature: Toward More Quantitative Data InterpretationFGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosisQuantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift Assay
P50
Q27716525-A1382A62-FBBC-4B0A-9036-BF505DF95031Q30381469-543A7897-18EA-434A-A17A-77426050AA56Q30384542-9ED3F484-607D-4553-BF44-D4980F03DBA0Q34544355-E3FAF6AE-12F9-4AB1-951B-F47C6B690CCAQ35235173-4A83A4A9-2F47-4598-B065-BE04EDB4AB2AQ35559260-C35325A9-2BB3-49D6-9185-4CA22DF58A58Q38843033-3309C96B-9935-49F7-8331-501CABDAA6F9Q40094796-3BC183CB-BB6A-419A-828C-957DB7D25E06Q41256404-6F19949F-26C8-4ED2-951D-31DA05E32C2BQ41366975-EAA5B279-5A40-4F4E-AA7A-FABEB3B5BAC9Q41788466-4B0552D5-A8B0-4FA9-A297-FDD29D9F859BQ42949449-1B660F91-0224-4CF4-BA52-40C0F275D2F8Q46248369-184D3F3E-AB56-47A6-A7BB-D277EC76400BQ47252031-7A196A00-F2A3-4E09-81C9-02858C588673Q47608818-5D5C104E-48C1-422F-85CC-90D0FEA52589Q50058544-A0FE64A4-BB5E-4467-806E-799B5CAA8F61Q52673303-D2977794-6250-44EE-95DB-268DE4F8047AQ58323039-897C5174-7A47-4C5F-A40A-13376B6718A8Q83987725-53862AA8-4AB7-446C-AC50-A44B59CC82DAQ84576308-059E7402-65C8-47E8-9F3D-0694A9A9039FQ84672448-32F88C55-D340-430C-9B3E-AF3CE45B7CAAQ85235032-8A3DFB60-2105-4E49-8DCB-F42035902CEAQ85642234-0919A313-94DA-4D9B-B248-B15EA2A1C5EBQ90295494-9E082F66-EB3A-4534-84FE-6E2ED2A5818CQ90736377-31ECD8CE-EB4F-4F0D-B55E-605B7141764FQ91009088-AFE71371-1E3F-4F41-8D5E-3DC146F3CE32Q92564992-93FFD5AB-33F5-4402-82E8-86EE768FEA75Q92999479-3EF33461-EC6A-45B1-A945-E7F2AB6F0311
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Brinton Seashore-Ludlow
@ast
Brinton Seashore-Ludlow
@en
Brinton Seashore-Ludlow
@es
Brinton Seashore-Ludlow
@nl
type
label
Brinton Seashore-Ludlow
@ast
Brinton Seashore-Ludlow
@en
Brinton Seashore-Ludlow
@es
Brinton Seashore-Ludlow
@nl
altLabel
Brinton A Seashore-Ludlow
@en
Brinton A Seashore-Ludlow
@nl
prefLabel
Brinton Seashore-Ludlow
@ast
Brinton Seashore-Ludlow
@en
Brinton Seashore-Ludlow
@es
Brinton Seashore-Ludlow
@nl
P106
P31
P496
0000-0001-8658-5967