about
Innate and Adaptive Immune Regulation During Chronic Viral InfectionsInterleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells.Delivery of cytokines by recombinant virus in early life alters the immune response to adult lung infection.Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8(+) Cytolytic T Cell Responses.RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity.Cell-Intrinsic gp130 Signaling on CD4+ T Cells Shapes Long-Lasting Antiviral ImmunityPlasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infectionLate interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection.Preexposure to CpG protects against the delayed effects of neonatal respiratory syncytial virus infection.Virally delivered cytokines alter the immune response to future lung infectionsCell-intrinsic IL-27 and gp130 cytokine receptor signaling regulates virus-specific CD4⁺ T cell responses and viral control during chronic infection.The role of T cells in the enhancement of respiratory syncytial virus infection severity during adult reinfection of neonatally sensitized mice.Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease developmentNeonatal antibody responses are attenuated by interferon-γ produced by NK and T cells during RSV infection.Delayed sequelae of neonatal respiratory syncytial virus infection are dependent on cells of the innate immune system.T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders.T-cell exhaustion due to persistent antigen: quantity not quality?Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.RSV 2005: Global impact, changing concepts, and new challenges.Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium.Genetic susceptibility to the delayed sequelae of neonatal respiratory syncytial virus infection is MHC dependent.Sustained T follicular helper cell response is essential for control of chronic viral infection.Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection.Allergic Airway Disease: More than Meets the IgE?Location, Location, Location: Localized Memory Cells Take Residence in the Allergic Lung.Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection.C1q restrains autoimmunity and viral infection by regulating CD8+T cell metabolismOrgan-specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentiumTargeting the ICOS/ICOS-L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates diseaseTherapeutic ICOS blockade reduces T follicular helper cells and improves allergic airway diseaseEnhanced frequency and function of follicular T cells in the tonsils of house dust mite-sensitized childrenT Cell-Intrinsic IL-6R Signaling Is Required for Optimal ICOS Expression and Viral Control during Chronic Infection
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
James Harker
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James Harker
@en
James Harker
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James Harker
@nl
James Harker
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type
label
James Harker
@ast
James Harker
@en
James Harker
@es
James Harker
@nl
James Harker
@sl
prefLabel
James Harker
@ast
James Harker
@en
James Harker
@es
James Harker
@nl
James Harker
@sl
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P21
P31
P496
0000-0002-0301-6898