Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

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Computer-Aided Drug Design in Epigenetics.Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma

P2860

Q55120002-55166DEE-9138-408B-9EDD-AB24DC3EE64E Q58617727-7F7454BB-6F24-42AB-BF4E-93CBFBF27DE3

P2860

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

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http://www.wikidata.org/entity/Q47583420

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

@en

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

@nl

type

Item

label

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

@en

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

@nl

prefLabel

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

@en

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

@nl

P1476

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues

@en

P2093

Chen Wang

http://www.w3.org/2001/XMLSchema#string

Hao Jiang

http://www.w3.org/2001/XMLSchema#string

Hao Zhang

http://www.w3.org/2001/XMLSchema#string

Hong Ding

http://www.w3.org/2001/XMLSchema#string

Hongru Tao

http://www.w3.org/2001/XMLSchema#string

Hualiang Jiang

http://www.w3.org/2001/XMLSchema#string

Kaixian Chen

http://www.w3.org/2001/XMLSchema#string

Liyan Yue

http://www.w3.org/2001/XMLSchema#string

Shijie Chen

http://www.w3.org/2001/XMLSchema#string

Wei Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Selective inhibition of BET bromodomains

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The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p

Effect of nitroxoline on angiogenesis and growth of human bladder cancer

Nitroxoline (8-hydroxy-5-nitroquinoline) is more a potent anti-cancer agent than clioquinol (5-chloro-7-iodo-8-quinoline)

Review of the literature and individual patients' data meta-analysis on efficacy and tolerance of nitroxoline in the treatment of uncomplicated urinary tract infections

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

P304

9352-9361

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P31

scholarly article

P356

10.1039/C7OB02369C

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Mingyue Zheng

Cheng Luo

Jing Xing

P577

2017-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29087414

http://www.w3.org/2001/XMLSchema#string

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

about

P2860

P2860

Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698