Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease.
about
FoxO Transcription Factors and Regenerative Pathways in Diabetes MellitusMini-review: emerging roles of microRNAs in the pathophysiology of renal diseasesAS101 prevents diabetic nephropathy progression and mesangial cell dysfunction: regulation of the AKT downstream pathwayTransforming growth factor-beta prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signalingTGF-β1, released by myofibroblasts, differentially regulates transcription and function of sodium and potassium channels in adult rat ventricular myocytesCaspase-3 activation as a bifurcation point between plasticity and cell death.The FOX transcription factors regulate vascular pathology, diabetes and TregsThe role of microRNAs in diabetic nephropathy.Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.High glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression.TGF-β regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells.FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.Oxidative stress mediates nephropathy in type Ia glycogen storage disease.Threonine 32 (Thr32) of FoxO3 is critical for TGF-β-induced apoptosis via Bim in hepatocarcinoma cells.MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes.Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrixMicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy.TGF-β converts apoptotic stimuli into the signal for Th9 differentiation.MicroRNAs and the glomerulusA microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cellsAngiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule CellsSmall-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner.Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's DiseaseHigh Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo ApproachIncreased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia.MicroRNA circuits in transforming growth factor-β actions and diabetic nephropathy.MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets.Hyperglycemia induces Toll like receptor 4 expression and activity in mouse mesangial cells: relevance to diabetic nephropathy.Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic NephropathyTriple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus.Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes"Sly as a FOXO": new paths with Forkhead signaling in the brainOutFOXOing disease and disability: the therapeutic potential of targeting FoxO proteinsRap1b GTPase ameliorates glucose-induced mitochondrial dysfunction.Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy.TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy.Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathyMicroRNAs: potential mediators and biomarkers of diabetic complications.A "FOXO" in sight: targeting Foxo proteins from conception to cancer.
P2860
Q26800615-43D3BDF2-2080-4630-8364-13901D7EDF2EQ28354033-04B41BF8-7D8A-4F4C-AD31-6259A27E5CE5Q28542507-55062415-B02F-4AFD-B1DB-5DB3F5D57FC1Q28569490-03CDA2FF-2801-468D-8712-AFE512D6A84BQ28573894-2366C006-A344-47C1-96ED-87ABECF9290AQ30446892-61B04CDA-3A9F-413F-914E-B07535EE3553Q33763033-BC9A05AF-577C-4892-9F2B-6B1EDD64442BQ34195411-1870535A-1655-4DB7-A556-7EA78A493B57Q34232095-DADF0772-1933-4B99-A75A-85BB2E95B243Q34552665-2748A8CE-CB09-4646-A7EE-77F6EAECCB77Q34598766-9D27BA5A-37AE-4F4F-AAAC-78A7B1A6E925Q34666156-D89EF290-C6BD-4083-B3C5-64B96A7043DFQ34807521-3180217E-C73B-4262-96D4-D65218EB595FQ35034543-213DF0D4-F982-43E0-8278-78D96F77EC65Q35110986-CA030A4B-9263-4362-BB62-86A8F2A07373Q35474548-E5AA0334-D345-4554-A1F5-D76025FEF41AQ35652362-822F23C5-81A7-4981-9724-FB605107C434Q35804221-A3E1F328-3E64-407D-9BCA-A9699CA4F751Q35903214-0C0F10B0-436B-411F-BBC9-3E5C1F3B3BE7Q35907222-16899F49-5943-4A8B-8E86-2E7C333E8668Q35915947-5BB3B7B3-666B-4CEA-9EA4-14647EA52954Q35920857-AEAE2098-F839-4D9E-A9B9-A92697661E2DQ35957393-BE60E55F-71E9-4AE9-B53A-3E6858B578A8Q36070777-B300C368-E765-4625-A73B-99B0EA21EA03Q36081651-1D561165-42E1-4650-B5EA-3E7BC32C1021Q36114692-18CF4C47-7691-4B11-A543-EFF8989E835AQ36124250-BBF95024-BA99-452C-A209-4FC6049F279DQ36166755-D52D146C-D103-4209-8549-77DBCB5C061EQ36312635-2AAA1CCE-4F1D-41C0-937A-8147D913E27AQ36656799-DC2681D8-7204-44CB-BAC1-A27D1B85C167Q36727444-1AF30F1C-8F1D-400D-A59A-0EA58BD278E0Q36844506-FDFCC8A8-ACC9-420C-A4A2-871BE0C06F81Q36944469-E3FF584C-D647-4C86-98C8-ECB94A701A3CQ36947037-5A716DF4-E292-4587-9945-EE247A8E85ADQ36985783-E38981BE-5BCB-43CD-A4E2-B38601699E05Q36994616-79EAD786-76F7-4531-8DC7-0C1039E245AFQ37045293-3B342746-28C7-464F-B194-F2064896E8C8Q37110591-BF41C5CF-2E66-4B8F-B2EA-01A99C543676Q37146727-DC378CA7-D966-4939-900F-0588CD10FD2DQ37153195-1F45D199-3F84-4CCE-9349-F705927D44D7
P2860
Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Role of the Akt/FoxO3a pathway ...... ed to diabetic kidney disease.
@en
Role of the Akt/FoxO3a pathway ...... ed to diabetic kidney disease.
@nl
type
label
Role of the Akt/FoxO3a pathway ...... ed to diabetic kidney disease.
@en
Role of the Akt/FoxO3a pathway ...... ed to diabetic kidney disease.
@nl
prefLabel
Role of the Akt/FoxO3a pathway ...... ed to diabetic kidney disease.
@en
Role of the Akt/FoxO3a pathway ...... ed to diabetic kidney disease.
@nl
P2093
P356
P1476
Role of the Akt/FoxO3a pathway ...... ted to diabetic kidney disease
@en
P2093
Linda Lanting
Marpadga A Reddy
Mickey C-T Hu
Rama Natarajan
Shu-Lian Li
Zhong-Gao Xu
P304
P356
10.1681/ASN.2006070754
P50
P577
2006-11-02T00:00:00Z