Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer's disease neurons.

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Impaired axonal retrograde trafficking of the retromer complex augments lysosomal deficits in Alzheimer's disease neurons.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

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Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

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Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

@en

Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

@nl

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Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

@en

Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

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P1476

Impaired axonal retrograde tra ...... n Alzheimer's disease neurons.

@en

P2093

Daniyal Aikal

http://www.w3.org/2001/XMLSchema#string

Prasad Tammineni

http://www.w3.org/2001/XMLSchema#string

Qian Cai

http://www.w3.org/2001/XMLSchema#string

Tuancheng Feng

http://www.w3.org/2001/XMLSchema#string

Yu Young Jeong

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P2860

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport

Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer

Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

Retromer

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation

Functional architecture of the retromer cargo-recognition complex

Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes.

P304

4352-4366

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P31

scholarly article

P356

10.1093/HMG/DDX321

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-08-14T00:00:00Z

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P698

28973312

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P921

Alzheimer's disease

P932

5886073

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