Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools.
about
The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer.Concentrative transport of antifolates mediated by the proton-coupled folate transporter (PCFT, SLC46A1); augmentation by a HEPES buffer.Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores).New tools for old drugs: Functional genetic screens to optimize current chemotherapy.Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
P2860
Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh
2017年學術文章
@zh-hant
name
Role of proton-coupled folate ...... and new pharmacological tools.
@en
Role of proton-coupled folate ...... and new pharmacological tools.
@nl
type
label
Role of proton-coupled folate ...... and new pharmacological tools.
@en
Role of proton-coupled folate ...... and new pharmacological tools.
@nl
prefLabel
Role of proton-coupled folate ...... and new pharmacological tools.
@en
Role of proton-coupled folate ...... and new pharmacological tools.
@nl
P2093
P2860
P50
P356
P1433
P1476
Role of proton-coupled folate ...... and new pharmacological tools.
@en
P2093
E A Struys
E Thunnissen
G J Peters
I B Muller
L H Matherly
P A Zucali
P2860
P304
P356
10.1093/ANNONC/MDX499
P577
2017-09-01T00:00:00Z