Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome. - Wikidata - awgldk - TriplyDB

Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.

Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.

http://www.wikidata.org/entity/Q47762736

about

The biological complexity of colorectal cancer: insights into biomarkers for early detection and personalized care Hereditary and familial colon cancer Q48P mutation in the hMLH1 gene associated with Lynch syndrome in three Hungarian families.Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer.Somatic hypermethylation of MSH2 is a frequent event in Lynch Syndrome colorectal cancers Genomic imprinting-an epigenetic gene-regulatory model.Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?Genetic predisposition to colorectal cancer: where we stand and future perspectives EPCAM germ line deletions as causes of Lynch syndrome in Spanish patients Gene discovery in familial cancer syndromes by exome sequencing: prospects for the elucidation of familial colorectal cancer type X.Clinical application of genetics in management of colorectal cancer.Causes and consequences of microsatellite instability in gastric carcinogenesis.Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases.Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms.Anticipation in lynch syndrome: where we are where we go Advances in the study of Lynch syndrome in China Hereditary gastrointestinal cancer syndromes.Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.Diagnostic Approach to Hereditary Colorectal Cancer Syndromes.Genetic testing for Lynch syndrome: family communication and motivation Clinical utility gene card for: Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) - update 2012.Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study.Update on Lynch syndrome genomics.A pilot study comparing protein expression in different segments of the normal colon and rectum and in normal colon versus adenoma in patients with Lynch syndrome Is it all Lynch syndrome?: An assessment of family history in individuals with mismatch repair-deficient tumors.Implementing screening for Lynch syndrome among patients with newly diagnosed colorectal cancer: summary of a public health/clinical collaborative meeting.Germline deletions in the EPCAM gene as a cause of Lynch syndrome - literature review Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one Evolving approach and clinical significance of detecting DNA mismatch repair deficiency in colorectal carcinoma.Lynch syndrome-associated extracolonic tumors are rare in two extended families with the same EPCAM deletion.Methylation Analysis of DNA Mismatch Repair Genes Using DNA Derived from the Peripheral Blood of Patients with Endometrial Cancer: Epimutation in Endometrial Carcinogenesis.Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC).Recent advances in understanding Lynch syndrome Recent insights into the pathogenesis of colorectal cancer.Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines.History, genetics, and strategies for cancer prevention in Lynch syndrome.Lynch syndrome diagnostics: decision-making process for germ-line testing.Epigenetic biomarkers in colorectal cancer diagnostics.EPCAM deletion carriers constitute a unique subgroup of Lynch syndrome patients.

P2860

Q28066460-E1D87A89-A6E7-459E-8222-A2CB104E1BAC Q28280647-D70D94BF-5AB9-403B-879C-F4B591579513 Q30413890-F10588E3-5418-4864-BCDA-83CAF4E66D8E Q33630653-09C9E1BE-C872-4ADC-8794-1DB28278F475 Q33795280-15429A19-C53A-4E89-BF15-4F7E95296309 Q33814499-D3DD4F6E-6FF0-4A10-9E8E-CE0F0C975CCD Q33892398-6E31C342-AC1A-4CFF-8B6A-A46F2B531104 Q34008801-5EA96A2E-0FEC-4930-AB04-2997031A8B7E Q34239731-42F375E2-5287-493D-9F53-F85532A6133B Q34269998-E741DFCD-B516-452A-9C56-2E060472D6D3 Q34378719-B7661331-B05B-41AF-B57B-34F1AAD5458F Q34589660-EF75E081-B145-48FA-8E37-67246F2124EB Q34756357-A927A1C5-072F-494A-8572-CF434E8A5B20 Q35053925-8BE2989B-74A0-4B94-982B-854152588C46 Q35560811-FB586B9E-9022-47DB-968A-42905DCD3A8F Q35716138-EE46CB1B-AA3B-4FDD-B69E-466AE159B221 Q35767560-1E776BD9-979B-46E3-9E3A-41D5B813C426 Q36051960-09AC2A79-B312-4D46-9457-2B3CC1A5AFE4 Q36303429-5CFE3C01-6FED-476B-B148-A53BFA2AAA89 Q36422099-9AAEC58B-1C35-4DFD-9FE7-F83C096D7DD2 Q36497317-5A445CDC-4FE1-4576-B57D-1694C8EBB125 Q36897112-3FDF2078-9245-4F64-89C4-B81CF8AA3B87 Q36990046-4C70E393-1DF3-4620-87F7-06710DF01072 Q37003013-482311A1-0C32-4B1D-8DFC-54D77143EE33 Q37073606-B6A8DCA0-F13F-463C-9155-7A546B601254 Q37146388-DDF05ED8-DC9D-4292-AD13-71F602E61F55 Q37152623-7430E1C5-A097-4A2D-B2B1-D5DBDCFDA531 Q37153032-45B2E8FA-5F27-4EC4-96A6-E65AE9602910 Q37224356-A1FE00DB-C0BE-43F5-9FA6-383D00E17872 Q37247809-9051F97B-5AA9-4420-955F-7D09EC86AD23 Q37248283-45F70701-2F56-4625-8DE6-295D01E4F141 Q37373629-C3A5732F-E9B2-46F3-843E-F5C7F1B1DB41 Q37507301-DD603AB7-39BE-4144-81C7-D9DB63EB3BD7 Q37577690-A1F4AE9A-CE3F-41EA-A1BC-C42696E536EB Q37604836-9D8AF7C7-0AEA-4819-8545-5097DA68C23A Q37659105-FD9A4AB0-89E2-4978-BF15-F32CA6C07846 Q37716875-F171D880-931B-4F88-9CB8-6E30CDD33FCE Q38000941-1887A2C3-9A2B-4966-B544-09A6134E6333 Q38018997-87902CC2-F0EB-4E20-A591-BCAB3E496FA7 Q38069531-60C51218-30BA-47F8-BF7F-FD25940A304A

P2860

Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.

http://www.wikidata.org/entity/Q47762736

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh

2009年學術文章

@zh-hant

name

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@en

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@nl

type

label

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@en

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@nl

prefLabel

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@en

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@nl

P1433

Q47762736-437CC69E-2F53-4404-9703-F0142A558FF0

P1476

Q47762736-4A293AF0-952E-45BD-894C-70A2F1F66EFA

P2093

Q47762736-218D097B-A86C-4ED6-B7FA-5E1009C8C101

Q47762736-36184C3C-47FE-43B9-9E8B-B53E89B3D931

Q47762736-4C4EE30D-D2FB-4701-9235-8A231E7E1B03

Q47762736-739214F9-508C-4939-A3EC-8199E8DA9431

Q47762736-7448046C-07B3-4680-A3A4-280E4EFB47BD

Q47762736-7EE35051-925C-43B5-BC10-CD5A28116D94

Q47762736-B2D570E7-9863-42C4-98D9-9E06D7ECD751

Q47762736-D011B9E0-BFC3-4DBE-86E0-1E3D3A0DFB75

Q47762736-D31A9782-7512-4D26-A75E-3014478C1EF0

Q47762736-D67D820D-BFC0-42C6-8684-8DD0EE9A163D

P304

Q47762736-500CB664-EC63-4D81-BE7B-FAD24C740FB7

P31

Q47762736-E5B19BFF-69FE-4FE9-B776-B38706E229C0

P356

Q47762736-F889CBAB-14AF-4EA5-ADF0-51032638E0B9

P433

Q47762736-9C191C33-7528-4E49-BF5D-4C593636CE95

P478

Q47762736-905A4A07-120B-4502-96C0-20BD80AB80C2

P50

Q47762736-125E2E81-BB23-484D-B624-C608A61F09BB

Q47762736-D1BF7574-A6BF-4A71-BC28-C9141F6DAB40

P577

Q47762736-BC7ADC0B-BACE-4AA7-9315-FE7A7C51AA51

P698

Q47762736-0824942D-6CB2-478C-9E2F-E250FF1EF1A5

P356

P1433

Genes, Chromosomes and Cancer

P1476

Germline hypermethylation of M ...... quent cause of Lynch syndrome.

@en

P2093

Harry Hollema

http://www.w3.org/2001/XMLSchema#string

Helga Westers

http://www.w3.org/2001/XMLSchema#string

Jan H Kleibeuker

http://www.w3.org/2001/XMLSchema#string

Krista Kooi

http://www.w3.org/2001/XMLSchema#string

Maran J W Olderode-Berends

http://www.w3.org/2001/XMLSchema#string

Marjolijn J L Ligtenberg

http://www.w3.org/2001/XMLSchema#string

Marloes L de Groote

http://www.w3.org/2001/XMLSchema#string

Paul O J Jager

http://www.w3.org/2001/XMLSchema#string

Renée C Niessen

http://www.w3.org/2001/XMLSchema#string

Trijnie Dijkhuizen

http://www.w3.org/2001/XMLSchema#string

P304

737-744

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/GCC.20678

http://www.w3.org/2001/XMLSchema#string

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

48

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

19455606

http://www.w3.org/2001/XMLSchema#string