Regulation of the human MAT2A gene encoding the catalytic alpha 2 subunit of methionine adenosyltransferase, MAT II: gene organization, promoter characterization, and identification of a site in the proximal promoter that is essential for its activi
about
Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferaseSp2 DNA binding activity and trans-activation are negatively regulated in mammalian cells.MAT2A mutations predispose individuals to thoracic aortic aneurysmsExpression of methionine adenosyltransferase 2A in renal cell carcinomas and potential mechanism for kidney carcinogenesis.Acetylation of MAT IIα represses tumour cell growth and is decreased in human hepatocellular cancerMethionine adenosyltransferase II-dependent histone H3K9 methylation at the COX-2 gene locus.An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling.Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells.Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells.Cullin 3 targets methionine adenosyltransferase IIα for ubiquitylation-mediated degradation and regulates colorectal cancer cell proliferation
P2860
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P2860
Regulation of the human MAT2A gene encoding the catalytic alpha 2 subunit of methionine adenosyltransferase, MAT II: gene organization, promoter characterization, and identification of a site in the proximal promoter that is essential for its activi
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Regulation of the human MAT2A ...... at is essential for its activi
@en
Regulation of the human MAT2A ...... at is essential for its activi
@nl
type
label
Regulation of the human MAT2A ...... at is essential for its activi
@en
Regulation of the human MAT2A ...... at is essential for its activi
@nl
prefLabel
Regulation of the human MAT2A ...... at is essential for its activi
@en
Regulation of the human MAT2A ...... at is essential for its activi
@nl
P2093
P2860
P356
P1476
Regulation of the human MAT2A ...... at is essential for its activi
@en
P2093
P2860
P304
P356
10.1074/JBC.M002347200
P407
P577
2000-12-21T00:00:00Z