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Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesisOxidative Stress during HIV Infection: Mechanisms and ConsequencesHuman herpes simplex virus: life cycle and development of inhibitorsAntiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication.Hepatitis C virus proteins activate NRF2/ARE pathway by distinct ROS-dependent and independent mechanisms in HUH7 cells.A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization.HCV and oxidative stress in the liver.Hydroxylamine derivatives for regulation of spermine and spermidine metabolism.Multisubunit RNA polymerases melt only a single DNA base pair downstream of the active site.Interaction of tRNA-derivatives and oligonucleotide primers with AZT-resistant mutants of HIV-1 reverse transcriptase.On the Reaction of Carbonyl Diphosphonic Acid with Hydroxylamine and O-alkylhydroxylamines: Unexpected Degradation of P-C-P Bridge.Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism.HCV core protein uses multiple mechanisms to induce oxidative stress in human hepatoma Huh7 cells.Pyridine hydroxamic acids are specific anti-HCV agents affecting HDAC6.Enantiomers of 3-methylspermidine selectively modulate deoxyhypusine synthesis and reveal important determinants for spermidine transport.Scaffold hopping: exploration of acetanilide-containing uracil analogues as potential NNRTIs.Selective inhibitor of histone deacetylase 6 (tubastatin A) suppresses proliferation of hepatitis C virus replicon in culture of human hepatocytes.Benzohydroxamic acids as potent and selective anti-HCV agents.N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase.Synthesis and anti-HIV properties of new carbamate prodrugs of AZT.Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells.The use of novel C-methylated spermidine derivatives to investigate the regulation of polyamine metabolism.Synthesis and biological characterization of novel charge-deficient spermine analogues.Hepatitis C virus NS5A protein modulates template selection by the RNA polymerase in in vitro system.[Low-molecular-weight regulators of biogenic polyamine metabolism affect cytokine production and expression of hepatitis С virus proteins in Huh7.5 human hepatocarcinoma cells].Evaluation of the antiprotozoan properties of 5'-norcarbocyclic pyrimidine nucleosides.Mutations conferring drug resistance affect eukaryotic expression of HIV type 1 reverse transcriptase.[Effect of Hepatitis C virus proteins on the production of proinflammatory and profibrotic cytokines in Huh7.5 human hepatoma cells].1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus.Versatile synthesis of oxime-containing acyclic nucleoside phosphonates--synthetic solutions and antiviral activity.Hepatitis C virus: The role of N-glycosylation sites of viral genotype 1b proteins for formation of viral particles in insect and mammalian cells.Specific features of HIV-1 integrase inhibition by bisphosphonate derivatives.The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives.Phosphoramidate derivatives of acyclovir: synthesis and antiviral activity in HIV-1 and HSV-1 models in vitro.[Synthesis and biological properties of pyrimidine 4'-fluoro nucleosides and 4'-fluoro uridine 5'-O-triphospate]Hepatitis C virus helicase/NTPase: an efficient expression system and new inhibitors.Biogenic polyamines spermine and spermidine activate RNA polymerase and inhibit RNA helicase of hepatitis C virus.New non-nucleoside inhibitors of hepatitis C virus RNA-dependent RNA polymerase.
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