Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract.Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat dietFatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells.Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson ModelIncreased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1.Anti-Inflammatory and Antioxidant Actions of N-Arachidonoyl Serotonin in RAW264.7 Cells.Spectroscopic and dynamic properties of arachidonoyl serotonin- β-lactoglobulin complex: A molecular modeling and chemometric study.Spectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands.Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1.New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain.Inhibition of FAAH confers increased stem cell migration via PPARαThe dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice.The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis.Effect of endocannabinoids on soybean lipoxygenase-1 activity.Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2.
P921
Q34204367-6AC3F592-7B89-4C48-B0E2-D7F1202E4125Q34644485-7D743E71-0596-4D8D-B12E-A278F85A506CQ35598600-1EBB04EA-A6FB-45ED-94AD-E55C6CC3FF72Q36510027-35B3C14D-0350-4576-928D-4D6527E9330BQ37046796-A4CCA24A-FADD-4DC6-9CF7-74299B86ED5AQ37208065-3D2FB19F-B7EF-477C-BB41-752EA51CE44BQ37371891-C403AB26-F3EB-4A2D-81ED-8F3837EA80F4Q37395994-28361AA5-CE3B-4282-9C73-A6CB38AC422FQ38795487-316920D4-3098-4C77-AA96-BD9C62EFBBC5Q39545088-119386AA-2619-4567-B177-910EC51546C6Q39561278-CACF90DA-B9B7-4A0E-B858-CC50EE85DB59Q39995855-590353A1-7BE0-453E-91F3-D655C104CFDDQ40047610-2F71E087-F39F-44B2-8570-E0966CB1C594Q42262304-6A111582-EBF3-4522-AB30-4D07D99C14FFQ43170128-1B8D3355-3151-4D65-AB25-9343A465C181Q43479534-110F1A2B-208E-4DCF-B9A7-807C0EF6434DQ46801025-E5CF5514-B9F4-4E20-9E84-43E65A255DEAQ48144352-E2C3813D-37C7-4238-A55F-359F287A4775
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
Arahidonoil serotonin
@sh
Arahidonoil serotonin
@sr
N-arachidonoylserotonin
@en
type
label
Arahidonoil serotonin
@sh
Arahidonoil serotonin
@sr
N-arachidonoylserotonin
@en
altLabel
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-eicosatetraenamide
@en
arachidonoyl serotonin
@en
prefLabel
Arahidonoil serotonin
@sh
Arahidonoil serotonin
@sr
N-arachidonoylserotonin
@en
P592
P6366
P661
P662
P683
P2017
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCC1=CNC2=C1C=C(C=C2)O
P2063
LMFA08020141
P2067
P231
187947-37-1
P233
CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCC1=CNC2=C1C=C(C=C2)O
P234
1S/C30H42N2O2/c1-2-3-4-5-6-7-8 ...... ,34)/b7-6-,10-9-,13-12-,16-15-
P235
QJDNHGXNNRLIGA-DOFZRALJSA-N
P274
C₃₀H₄₂N₂O₂
P592
CHEMBL191534
P6366
2781422075