Synthesis and evaluation of xanthone derivatives as acid sphingomyelinase inhibitors: potential treatment for UV-induced skin damage.

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Synthesis and evaluation of xanthone derivatives as acid sphingomyelinase inhibitors: potential treatment for UV-induced skin damage.

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2017 nî lūn-bûn

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Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

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Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

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Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

@en

Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

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Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

@en

Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

@nl

P1476

Synthesis and evaluation of xa ...... nt for UV-induced skin damage.

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P2093

Biao Gao

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Jibin Dong

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Jinxin Wang

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Kan Yang

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Minghui Wang

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Xianjun Ming

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Zhipeng Huang

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P2860

Structure of Human Acid Sphingomyelinase Reveals the Role of the Saposin Domain in Activating Substrate Hydrolysis

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo.

Analysis of Molecular Species Profiles of Ceramide-1-phosphate and Sphingomyelin Using MALDI-TOF Mass Spectrometry.

Glycosphingolipids and cell death: one aim, many ways

Ultraviolet (UV) and hydrogen peroxide activate ceramide-ER stress-AMPK signaling axis to promote retinal pigment epithelium (RPE) cell apoptosis.

Crystal structure of mammalian acid sphingomyelinase

Small molecule inhibitors of acid sphingomyelinase.

Ceramide-orchestrated signalling in cancer cells.

Lipid deregulation in UV irradiated skin cells: Role of 25-hydroxycholesterol in keratinocyte differentiation during photoaging.

1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation.

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1887-1898

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scholarly article

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10.4155/FMC-2017-0102

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2017-10-27T00:00:00Z

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29076348

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