New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin.
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A conserved TLR5 binding and activation hot spot on flagellinContrasting roles for TLR ligands in HIV-1 pathogenesis.Salmonella enterica serovar Typhimurium vaccine strains expressing a nontoxic Shiga-like toxin 2 derivative induce partial protective immunity to the toxin expressed by enterohemorrhagic Escherichia coli.Lipid motif of a bacterial antigen mediates immune responses via TLR2 signaling.Rapid vaccination using an acetalated dextran microparticulate subunit vaccine confers protection against triplicate challenge by bacillus anthracis.Antigenicity and immunogenicity of Plasmodium vivax merozoite surface protein-3.Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans?Dissimilar properties of two recombinant Lactobacillus acidophilus strains displaying Salmonella FliC with different anchoring motifsSalmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine.Construction and immunological evaluation of dual cell surface display of HIV-1 gag and Salmonella enterica serovar Typhimurium FliC in Lactobacillus acidophilus for vaccine delivery.Flagellin as an adjuvant: cellular mechanisms and potential.Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responsesA chimeric protein-based malaria vaccine candidate induces robust T cell responses against Plasmodium vivax MSP119.Protective humoral immunity elicited by a needle-free malaria vaccine comprised of a chimeric Plasmodium falciparum circumsporozoite protein and a Toll-like receptor 5 agonist, flagellin.A recombinant multi-antigen vaccine formulation containing Babesia bovis merozoite surface antigens MSA-2a1, MSA-2b and MSA-2c elicits invasion-inhibitory antibodies and IFN-γ producing cellsImaging murine NALT following intranasal immunization with flagellin-modified circumsporozoite protein malaria vaccines.Immunogenicity of recombinant proteins consisting of Plasmodium vivax circumsporozoite protein allelic variant-derived epitopes fused with Salmonella enterica Serovar Typhimurium flagellin.Immunogenicity of a prime-boost vaccine containing the circumsporozoite proteins of Plasmodium vivax in rodents.Assessment of the adjuvant activity of mesoporous silica nanoparticles in recombinant Mycoplasma hyopneumoniae antigen vaccines.Prophylactic and therapeutic implications of toll-like receptor ligands.N-terminal Plasmodium vivax merozoite surface protein-1, a potential subunit for malaria vivax vaccine.Utilizing bacterial flagellins against infectious diseases and cancers.Reconstitution of a functional Toll-like receptor 5 binding site in Campylobacter jejuni flagellin.Bacterial flagellin-a potent immunomodulatory agent.Association of TLR variants with susceptibility to Plasmodium vivax malaria and parasitemia in the Amazon region of Brazil.Cloning of fliC Gene From Salmonella typhimurium in the Expression Vector pVAX1 and Evaluation of its Expression in Eukaryotic Cells.Structure-function relationships of protein-lipopeptide complexes and influence on immunogenicity.Malaria vaccine adjuvants: latest update and challenges in preclinical and clinical research.TLR4 ligands augment antigen-specific CD8+ T lymphocyte responses elicited by a viral vaccine vector.Vaccine Containing the Three Allelic Variants of the Plasmodium vivax Circumsporozoite Antigen Induces Protection in Mice after Challenge with a Transgenic Rodent Malaria Parasite.A safety study of a B-class CpG ODN in Sprague-Dawley rats.Induction of cell-mediated immune responses to peptide antigens of P. vivax in microparticles using intranasal immunization.TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium.Prime-boost vaccination with recombinant protein and adenovirus-vector expressing Plasmodium vivax circumsporozoite protein (CSP) partially protects mice against Pb/Pv sporozoite challenge.Anti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10.New adjuvants in evolving vaccine strategies.Crystal structure of Bacillus cereus flagellin and structure-guided fusion-protein designs.
P2860
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P2860
New malaria vaccine candidates based on the Plasmodium vivax Merozoite Surface Protein-1 and the TLR-5 agonist Salmonella Typhimurium FliC flagellin.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
New malaria vaccine candidates ...... la Typhimurium FliC flagellin.
@en
New malaria vaccine candidates ...... la Typhimurium FliC flagellin.
@nl
type
label
New malaria vaccine candidates ...... la Typhimurium FliC flagellin.
@en
New malaria vaccine candidates ...... la Typhimurium FliC flagellin.
@nl
prefLabel
New malaria vaccine candidates ...... la Typhimurium FliC flagellin.
@en
New malaria vaccine candidates ...... la Typhimurium FliC flagellin.
@nl
P2093
P50
P921
P1433
P1476
New malaria vaccine candidates ...... lla Typhimurium FliC flagellin
@en
P2093
Adelaide José Vaz
Bruna O Carvalho
Catarina J M Braga
Fabio T M Costa
Irene S Soares
Mauricio M Rodrigues
Noeli Maria Espíndola
P304
P356
10.1016/J.VACCINE.2008.08.070
P407
P577
2008-09-18T00:00:00Z