Cellular and molecular abnormalities in severe congenital neutropenia predisposing to leukemia.
about
LEF-1 is a decisive transcription factor in neutrophil granulopoiesisCyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes.Severe congenital neutropenia: genetics and pathogenesis.GFI1 is repressed by p53 and inhibits DNA damage-induced apoptosis.Granulocyte colony-stimulating factor and leukemogenesis.Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis.Polymorphisms in the promoter region of neutrophil elastase gene and lung cancer riskGenetic and molecular diagnosis of severe congenital neutropenia.G-CSF receptor (CSF3R) mutations in X-linked neutropenia evolving to acute myeloid leukemia or myelodysplasia.Neutropenia and primary immunodeficiency diseases.A Truncated Granulocyte Colony-stimulating Factor Receptor (G-CSFR) Inhibits Apoptosis Induced by Neutrophil Elastase G185R Mutant: IMPLICATION FOR UNDERSTANDING CSF3R GENE MUTATIONS IN SEVERE CONGENITAL NEUTROPENIA.Severe congenital neutropenias.The cellular and molecular mechanisms for neutropenia in Barth syndrome.Increased CCAAT enhancer-binding protein epsilon (C/EBPepsilon) expression and premature apoptosis in myeloid cells expressing Gfi-1 N382S mutant associated with severe congenital neutropenia.Tyrosine 729 of the G-CSF receptor controls the duration of receptor signaling: involvement of SOCS3 and SOCS1.Aberrant subcellular targeting of the G185R neutrophil elastase mutant associated with severe congenital neutropenia induces premature apoptosis of differentiating promyelocytes.Understanding, treating and avoiding hematological disease: better medicine through mathematics?Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia.Periodontal status in two siblings with severe congenital neutropenia: diagnosis and mutational analysis of the cases.Heterogeneous expression pattern of pro- and anti-apoptotic factors in myeloid progenitor cells of patients with severe congenital neutropenia treated with granulocyte colony-stimulating factor.
P2860
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P2860
Cellular and molecular abnormalities in severe congenital neutropenia predisposing to leukemia.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@en
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@nl
type
label
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@en
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@nl
prefLabel
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@en
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@nl
P2093
P1476
Cellular and molecular abnorma ...... enia predisposing to leukemia.
@en
P2093
Andrew A G Aprikyan
David C Dale
Elin Rodger
Laurence A Boxer
Pavel Aprikian
Steven Stein
Tatyana Kutyavin
W Conrad Liles
P304
P356
10.1016/S0301-472X(03)00048-1
P577
2003-05-01T00:00:00Z