The broad spectrum antiviral nucleoside ribavirin as a substrate for a viral RNA capping enzyme.
about
Structure and functionality in flavivirus NS-proteins: perspectives for drug designA Sensitive and Robust High-Throughput Screening Assay for Inhibitors of the Chikungunya Virus nsP1 Capping EnzymeThe RNA capping machinery as an anti-infective targetThe flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structureMutagenic Effects of Ribavirin on Hepatitis E Virus-Viral Extinction versus Selection of Fitness-Enhancing MutationsVirtual high-throughput screening identifies mycophenolic acid as a novel RNA capping inhibitorThe immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzymeInhibition of a metal-dependent viral RNA triphosphatase by decavanadateIdentification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approachThe antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro.Enzymatic synthesis of RNAs capped with nucleotide analogues reveals the molecular basis for substrate selectivity of RNA capping enzyme: impacts on RNA metabolism.Chlorogenic acid inhibits the replication and viability of enterovirus 71 in vitroResveratrol inhibits enterovirus 71 replication and pro-inflammatory cytokine secretion in rhabdosarcoma cells through blocking IKKs/NF-κB signaling pathway.Orthopoxvirus targets for the development of antiviral therapies.Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase.The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruziCap-dependent translation initiation factor eIF4E: an emerging anticancer drug target.Comparison of three dimensional synergistic analyses of percentage versus logarithmic data in antiviral studies.Effective lethal mutagenesis of influenza virus by three nucleoside analogs.5'-Phospho-RNA Acceptor Specificity of GDP Polyribonucleotidyltransferase of Vesicular Stomatitis Virus in mRNA CappingIn-vitro antiviral efficacy of ribavirin and interferon-alpha against canine distemper virus.Determining Ribavirin's mechanism of action against Lassa virus infection.Magnesium-binding studies reveal fundamental differences between closely related RNA triphosphatases.mRNA-Seq reveals accumulation followed by reduction of small nuclear and nucleolar RNAs in yeast exposed to antiviral ribavirin.Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.Inhibitory effect of a nucleotide analog on infectious salmon anemia virus infection.Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes.
P2860
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P2860
The broad spectrum antiviral nucleoside ribavirin as a substrate for a viral RNA capping enzyme.
description
2004 nî lūn-bûn
@nan
2004年の論文
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2004年学术文章
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2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
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@zh-hant
name
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@en
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@nl
type
label
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@en
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@nl
prefLabel
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@en
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@nl
P2860
P356
P1476
The broad spectrum antiviral n ...... or a viral RNA capping enzyme.
@en
P2093
Isabelle Bougie
Martin Bisaillon
P2860
P304
22124-22130
P356
10.1074/JBC.M400908200
P407
P577
2004-03-22T00:00:00Z