The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway.
about
Function and Regulation of Heterotrimeric G Proteins during ChemotaxisActivators of G protein signaling exhibit broad functionality and define a distinct core signaling triadB Lymphocyte-Specific Loss of Ric-8A Results in a Gα Protein Deficit and Severe Humoral Immunodeficiency.Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cellsA Worldwide Competition to Compare the Speed and Chemotactic Accuracy of Neutrophil-Like CellsPhosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence.Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration.Homer3 regulates the establishment of neutrophil polarityGαi2- and Gαi3-deficient mice display opposite severity of myocardial ischemia reperfusion injuryDefective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3)A chemical biology approach demonstrates G protein βγ subunits are sufficient to mediate directional neutrophil chemotaxis.Implications of non-canonical G-protein signaling for the immune systemHeterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeletonUsing light to shape chemical gradients for parallel and automated analysis of chemotaxis.LGN Directs Interphase Endothelial Cell Behavior via the Microtubule Network.A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal Transduction Network.Regulation of Chemokine Signal Integration by Activator of G-Protein Signaling 4 (AGS4).c-Rel Regulates Inscuteable Gene Expression during Mouse Embryonic Stem Cell Differentiation.Crossroads of PI3K and Rac pathways.Novel therapeutic roles for surfactant-inositols and -phosphatidylglycerols in a neonatal piglet ARDS model. A translational study.The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity.The Spindle Orientation Machinery Beyond Mitosis: When Cell Specialization Demands Polarization.The Nuclear Protein IκBζ Forms a Transcriptionally Active Complex with Nuclear Factor-κB (NF-κB) p50 and the Lcn2 Promoter via the N- and C-terminal Ankyrin Repeat Motifs.Structural basis for the recognition of the scaffold protein Frmpd4/Preso1 by the TPR domain of the adaptor protein LGN.Ric-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis.Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3.Connecting G protein signaling to chemoattractant-mediated cell polarity and cytoskeletal reorganization.Insc:LGN tetramers promote asymmetric divisions of mammary stem cells.
P2860
Q26771178-457B924A-294B-4628-A7AC-2F33800F1709Q26999408-052103FF-6190-4AC8-A593-4D5A1200343CQ27302329-207B3537-A111-416E-A0FB-7DAA5995815AQ27311545-9D92DE15-AE36-41C0-A614-0E8FF89ED524Q27312036-84E634BF-C3F2-4D8F-BE73-793E633D0632Q30564033-94930851-CBC6-4C55-BA1C-81AD219F1945Q30585391-EC25B26A-9AED-4A60-9477-9666F1BA5394Q30651005-3E5B0070-2F16-44B2-B851-A54E8A33127EQ33654968-21280958-5617-4EC4-957D-20F53FDEAE71Q33675851-779C86EC-FD6E-4DF7-B240-DD192436EF36Q33793018-E2439EDE-6029-4062-9963-3BA44FFAF0A4Q33978840-910FDBE2-843D-46A0-B9D9-C8BA04ECFDEAQ34348735-0F200BB8-D24E-4888-A602-6BC0E58E0668Q35577198-46AE7A67-684C-40F8-8113-A318E55FAF95Q35785445-5749F9C9-1028-4B00-9CF5-2CD3609CA590Q36010851-231A49B1-CBEB-47E8-82FA-3C6AE096CC78Q37664759-3BE5739C-2CB0-45A0-A2F3-5D916D28901EQ38378086-4085761F-0ADA-4815-A5A1-FD529467D449Q38459968-3D022C24-A0C8-424C-BF2D-11B4902FEBE8Q38634777-5059D360-EF6F-409E-898E-4426645FC04AQ38806373-BF763101-A0B0-4ECB-9E6D-C4E21237D114Q39363658-C8E999ED-00B5-45AE-B5D1-363E4DDAEFEFQ41161836-A8FF9F6F-3E69-4535-9ABE-8265E79DF3F6Q41460052-FA345922-1896-4F70-91D9-B05746860DEFQ42505499-5BBD8931-403C-4523-B73D-5F524C8341A6Q46339583-2A83FC7F-FFE7-4C4C-8F22-30F56627AE61Q46394709-764B73CA-DCCC-4757-BEE4-48BA36AFE484Q52361062-ECFD5FCA-1866-4CF5-B988-6A17C67DC90E
P2860
The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
The cell polarity protein mIns ...... l G protein signaling pathway.
@en
The cell polarity protein mIns ...... l G protein signaling pathway.
@nl
type
label
The cell polarity protein mIns ...... l G protein signaling pathway.
@en
The cell polarity protein mIns ...... l G protein signaling pathway.
@nl
prefLabel
The cell polarity protein mIns ...... l G protein signaling pathway.
@en
The cell polarity protein mIns ...... l G protein signaling pathway.
@nl
P2093
P1433
P1476
The cell polarity protein mIns ...... l G protein signaling pathway.
@en
P2093
Hideki Sumimoto
Junya Hayase
Masatoshi Nomura
Ryoichi Takayanagi
Sachiko Kamakura
Yuko Iwakiri
P304
P356
10.1016/J.DEVCEL.2013.06.008
P407
P577
2013-07-25T00:00:00Z