Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas. - Wikidata - awgldk - TriplyDB

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

http://www.wikidata.org/entity/Q47992753

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Profiling critical cancer gene mutations in clinical tumor samples To BRAF or not to BRAF: is that even a question anymore?MAPK pathway activation in pilocytic astrocytoma The molecular biology of WHO grade I astrocytomas Will kinase inhibitors make it as glioblastoma drugs?Pathological and molecular advances in pediatric low-grade astrocytoma BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition Pilocytic astrocytoma: a disease with evolving molecular heterogeneity Reactive retinal astrocytic tumors (so-called vasoproliferative tumors): histopathologic, immunohistochemical, and genetic studies of four cases.A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.Adult pilocytic astrocytomas: clinical features and molecular analysis Clinical, radiological, histological and molecular characteristics of paediatric epithelioid glioblastoma Glioma diagnostics and biomarkers: an ongoing challenge in the field of medicine and science Pediatric low-grade gliomas: how modern biology reshapes the clinical field.BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model.BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications.Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas.Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors Differences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas.Temporal lobe pleomorphic xanthoastrocytoma and acquired BRAF mutation in an adolescent with the constitutional 22q11.2 deletion syndrome.Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.A multivariate analysis of factors determining tumor progression in childhood low-grade glioma: a population-based cohort study (CCLG CNS9702)MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas.The mTOR signaling pathway as a treatment target for intracranial neoplasms Notch signaling activation in pediatric low-grade astrocytoma The BRAF kinase domain promotes the development of gliomas in vivo.Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells.Incidence of kiaa1549-braf fusion gene in Egyptian pediatric low grade glioma.Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.Challenging issues in pediatric oncology KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.Molecular Profiling of a Rare Rosette-Forming Glioneuronal Tumor Arising in the Spinal Cord A pilot study using carboplatin, vincristine, and temozolomide in children with progressive/symptomatic low-grade glioma: a Children's Oncology Group study†Novel BRAF Alteration in a Sporadic Pilocytic Astrocytoma.Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum

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Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

http://www.wikidata.org/entity/Q47992753

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Activation of the ERK/MAPK pat ...... fossa pilocytic astrocytomas.

@en

Activation of the ERK/MAPK pat ...... fossa pilocytic astrocytomas.

@nl

type

label

Activation of the ERK/MAPK pat ...... fossa pilocytic astrocytomas.

@en

Activation of the ERK/MAPK pat ...... fossa pilocytic astrocytomas.

@nl

prefLabel

Activation of the ERK/MAPK pat ...... fossa pilocytic astrocytomas.

@en

Activation of the ERK/MAPK pat ...... fossa pilocytic astrocytomas.

@nl

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The Journal of Pathology

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Activation of the ERK/MAPK pat ...... r fossa pilocytic astrocytomas

@en

P2093

Alberto Broniscer

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Amar Gajjar

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Babatunji W Ogunkolade

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Bryan D Young

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David W Ellison

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Geoff Neale

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James Dalton

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Jing Ma

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Rowena L Carter

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Simon Bailey

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P2860

Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.

Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas.

Loss of NF1 alleles distinguish sporadic from NF1-associated pilocytic astrocytomas.

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172-181

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scholarly article

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10.1002/PATH.2558

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2

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218

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Ruth G. Tatevossian

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2009-06-01T00:00:00Z

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24284663

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19373855

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