The requirement of localized, CR2-mediated, alternative pathway activation of complement for covalent deposition of C3 fragments on normal B cells.
about
The role of complement in the acquired immune response.Germinal center initiation, variable gene region hypermutation, and mutant B cell selection without detectable immune complexes on follicular dendritic cells.The versatile functions of complement C3-derived ligands.The B cell receptor itself can activate complement to provide the complement receptor 1/2 ligand required to enhance B cell immune responses in vivo.Spontaneous complement activation on human B cells results in localized membrane depolarization and the clustering of complement receptor type 2 and C3 fragments.CR2-mediated activation of the complement alternative pathway results in formation of membrane attack complexes on human B lymphocytes.The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes.
P2860
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P2860
The requirement of localized, CR2-mediated, alternative pathway activation of complement for covalent deposition of C3 fragments on normal B cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
The requirement of localized, ...... 3 fragments on normal B cells.
@en
The requirement of localized, ...... 3 fragments on normal B cells.
@nl
type
label
The requirement of localized, ...... 3 fragments on normal B cells.
@en
The requirement of localized, ...... 3 fragments on normal B cells.
@nl
prefLabel
The requirement of localized, ...... 3 fragments on normal B cells.
@en
The requirement of localized, ...... 3 fragments on normal B cells.
@nl
P2093
P2860
P1433
P1476
The requirement of localized, ...... 3 fragments on normal B cells.
@en
P2093
P2860
P304
P356
10.1046/J.1365-2567.1998.00429.X
P577
1998-02-01T00:00:00Z