The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
about
Differential behavior of missense mutations in the intersubunit contact domain of the human pyruvate kinase M2 isozymeStructure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemiaModulation of allostery of pyruvate kinase by shifting of an ensemble of microstates.Dominant negative role of the glutamic acid residue conserved in the pyruvate kinase M(1) isozyme in the heterotropic allosteric effect involving fructose-1,6-bisphosphate.Exploring the limits of the usefulness of mutagenesis in studies of allosteric mechanisms.Identification of regions of rabbit muscle pyruvate kinase important for allosteric regulation by phenylalanine, detected by H/D exchange mass spectrometry.Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation.Mechanisms of Mendelian dominance.
P2860
Q24654900-21151250-95B5-40EC-A31A-A8330343B979Q27638876-BA95FD8A-9F03-47D3-BDBA-5C05AFA5AC5DQ34593844-711E7B7D-BC29-40EA-97B0-657E507F3B40Q38314012-250CB95A-A557-4842-8381-06D4EDDE14BBQ38811496-59BD377B-ABB7-4D09-8F82-53918946865BQ39726334-9B49CD6A-A6BD-4523-BF16-17FE07A1240BQ39990007-AEC16D89-42D9-4076-9532-03E5609167B8Q48326258-042411FA-89C8-48C5-B537-0495A9BB7E1E
P2860
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@en
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@nl
type
label
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@en
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@nl
prefLabel
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@en
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@nl
P2860
P356
P1476
The negative dominant effects of T340M mutation on mammalian pyruvate kinase.
@en
P2093
P2860
P304
14772-14779
P356
10.1074/JBC.273.24.14772
P407
P577
1998-06-01T00:00:00Z