Lingual deficits in BDNF and NT3 mutant mice leading to gustatory and somatosensory disturbances, respectively.
about
Anterograde tracing method using DiI to label vagal innervation of the embryonic and early postnatal mouse gastrointestinal tractCharacterization of stem/progenitor cell cycle using murine circumvallate papilla taste bud organoid.BDNF and NT4 play interchangeable roles in gustatory developmentBDNF is required for taste axon regeneration following unilateral chorda tympani nerve section.Expanded terminal fields of gustatory nerves accompany embryonic BDNF overexpression in mouse oral epithelia.Fungiform taste bud degeneration in C57BL/6J mice following chorda-lingual nerve transectionEach sensory nerve arising from the geniculate ganglion expresses a unique fingerprint of neurotrophin and neurotrophin receptor genes.Neuron/target plasticity in the peripheral gustatory system.Epibranchial placode-derived neurons produce BDNF required for early sensory neuron development.BDNF is required for the survival of differentiated geniculate ganglion neurons.Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling.Lingual and palatal gustatory afferents each depend on both BDNF and NT-4, but the dependence is greater for lingual than palatal afferentsTarget pioneering and early morphology of the murine chorda tympani.Factors that regulate embryonic gustatory development.The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development.Single Lgr5- or Lgr6-expressing taste stem/progenitor cells generate taste bud cells ex vivo.Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system.Taste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulationShrinkage of ipsilateral taste buds and hyperplasia of contralateral taste buds following chorda tympani nerve transectionEpithelial overexpression of BDNF and NT4 produces distinct gustatory axon morphologies that disrupt initial targeting.Targeted taste cell-specific overexpression of brain-derived neurotrophic factor in adult taste buds elevates phosphorylated TrkB protein levels in taste cells, increases taste bud size, and promotes gustatory innervation.Refinement of innervation accuracy following initial targeting of peripheral gustatory fibersDevelopmental time course of peripheral cross-modal sensory interaction of the trigeminal and gustatory systems.Neurotrophin-4 is more potent than brain-derived neurotrophic factor in promoting, attracting and suppressing geniculate ganglion neurite outgrowth.Mice lacking the p75 receptor fail to acquire a normal complement of taste buds and geniculate ganglion neurons by adulthoodVariant BDNF Val66Met polymorphism affects extinction of conditioned aversive memory.Fate mapping of mammalian embryonic taste bud progenitorsEpithelial-derived brain-derived neurotrophic factor is required for gustatory neuron targeting during a critical developmental periodDiverse dependencies of developing Merkel innervation on the trkA and both full-length and truncated isoforms of trkC.Alterations in size, number, and morphology of gustatory papillae and taste buds in BDNF null mutant mice demonstrate neural dependence of developing taste organs.Neurotrophin-4 regulates the survival of gustatory neurons earlier in development using a different mechanism than brain-derived neurotrophic factorHormones in the naso-oropharynx: endocrine modulation of taste and smellBrain-derived neurotrophic factor attracts geniculate ganglion neurites during embryonic targetingTaste cell formation does not require gustatory and somatosensory innervation.Ephrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae.Embryonic origin of gustatory cranial sensory neurons.Taste Bud-Derived BDNF Is Required to Maintain Normal Amounts of Innervation to Adult Taste Buds.Bmp signalling in filiform tongue papillae development.
P2860
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P2860
Lingual deficits in BDNF and NT3 mutant mice leading to gustatory and somatosensory disturbances, respectively.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Lingual deficits in BDNF and N ...... ry disturbances, respectively.
@en
Lingual deficits in BDNF and N ...... ry disturbances, respectively.
@nl
type
label
Lingual deficits in BDNF and N ...... ry disturbances, respectively.
@en
Lingual deficits in BDNF and N ...... ry disturbances, respectively.
@nl
prefLabel
Lingual deficits in BDNF and N ...... ry disturbances, respectively.
@en
Lingual deficits in BDNF and N ...... ry disturbances, respectively.
@nl
P2093
P1433
P1476
Lingual deficits in BDNF and N ...... ory disturbances, respectively
@en
P2093
P304
P407
P577
1997-04-01T00:00:00Z