Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on Cognition. - Wikidata - awgldk - TriplyDB

Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on Cognition.

Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on Cognition.

http://www.wikidata.org/entity/Q48074126

about

Perillyl Alcohol and Its Drug-Conjugated Derivatives as Potential Novel Methods of Treating Brain Metastases The therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease.Changes in insulin and insulin signaling in Alzheimer's disease: cause or consequence?Insulin resistance, dyslipidemia, and apolipoprotein E interactions as mechanisms in cognitive impairment and Alzheimer's disease Intranasal insulin alleviates cognitive deficits and amyloid pathology in young adult APPswe/PS1dE9 mice Passage through the Ocular Barriers and Beneficial Effects in Retinal Ischemia of Topical Application of PACAP1-38 in Rodents.Long-term treatment with intranasal insulin ameliorates cognitive impairment, tau hyperphosphorylation, and microglial activation in a streptozotocin-induced Alzheimer's rat model.Cerebral cortex: a target and source of insulin?The SAMP8 mouse for investigating memory and the role of insulin in the brain.Impact of Single or Repeated Dose Intranasal Zinc-free Insulin in Young and Aged F344 Rats on Cognition, Signaling, and Brain Metabolism.Targeting Mediators of Smoking Persistence with Intranasal Insulin.Insulin delivery to the brain using intracranial implantation of alginate-encapsulated pancreatic islets.Reduction of smoking urges with intranasal insulin: a randomized, crossover, placebo-controlled clinical trial.Novel calcium-related targets of insulin in hippocampal neurons.Intranasal Insulin Transport is Preserved in Aged SAMP8 Mice and is Altered by Albumin and Insulin Receptor Inhibition.Expression of a Constitutively Active Human Insulin Receptor in Hippocampal Neurons Does Not Alter VGCC Currents.Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice.

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Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on Cognition.

http://www.wikidata.org/entity/Q48074126

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Central Nervous System Deliver ...... take and Effects on Cognition.

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Central Nervous System Deliver ...... take and Effects on Cognition.

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type

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Central Nervous System Deliver ...... take and Effects on Cognition.

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Central Nervous System Deliver ...... take and Effects on Cognition.

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Central Nervous System Deliver ...... take and Effects on Cognition.

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Central Nervous System Deliver ...... take and Effects on Cognition.

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Journal of Alzheimer's Disease

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Central Nervous System Deliver ...... take and Effects on Cognition.

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P2093

Isabel A Hujoel

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John E Morley

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Junghyun Kim

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Kristin M Bullock

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Michael L Niehoff

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Susan A Farr

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Tami Wolden-Hanson

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Therese S Salameh

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P2860

The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

IL-15 overexpression promotes endurance, oxidative energy metabolism, and muscle PPARδ, SIRT1, PGC-1α, and PGC-1β expression in male mice.

Sex and ApoE genotype differences in treatment response to two doses of intranasal insulin in adults with mild cognitive impairment or Alzheimer's disease.

Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice

Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.

Intranasal administration as a route for drug delivery to the brain: evidence for a unique pathway for albumin.

Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Aβ generation.

Intranasal insulin improves memory in humans.

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715-728

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10.3233/JAD-150307

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3

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47

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William A Banks

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2015-08-01T00:00:00Z

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26401706

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6080853

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