Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.
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Mucins in cancer: function, prognosis and therapyCyclooxygenase-deficient pancreatic cancer cells use exogenous sources of prostaglandins.Mucins: a new family of epigenetic biomarkers in epithelial cancers.Genome wide analysis of the bovine mucin genes and their gastrointestinal transcription profile.Chronic anti-inflammatory drug therapy inhibits gel-forming mucin production in a murine xenograft model of human pseudomyxoma peritoneiPrognostic significance of mucin expression in urothelial bladder cancer.The application of methylation specific electrophoresis (MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells.The silence of MUC2 mRNA induced by promoter hypermethylation associated with HBV in Hepatocellular CarcinomaMuc5ac mucin expression during rat skin development.The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling.Emerging potential of natural products for targeting mucins for therapy against inflammation and cancer.Epigenetic regulation of mucin genes in human cancersA common MUC5B promoter polymorphism and pulmonary fibrosis.Epigenetics in lung fibrosis: from pathobiology to treatment perspective.Vibrio vulnificus VvpE inhibits mucin 2 expression by hypermethylation via lipid raft-mediated ROS signaling in intestinal epithelial cellsCurrent evidence for histone deacetylase inhibitors in pancreatic cancer.Coordinate regulation of the gel-forming mucin genes at chromosome 11p15.5.Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathwaysMucins and Wnt/β-catenin signaling in gastrointestinal cancers: an unholy nexus.Potential prognostic biomarkers of pancreatic cancerHistone deacetylases: a saga of perturbed acetylation homeostasis in cancer.Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions.MUC2 expression is an adverse prognostic factor in superficial gastroesophageal adenocarcinomas.Proteomic mucin profiling for the identification of cystic precursors of pancreatic cancer.The importance of epigenetics in the development of chronic obstructive pulmonary disease.Mucins in human neoplasms: clinical pathology, gene expression and diagnostic application.Mucin as a therapeutic target in pseudomyxoma peritonei.The genetic and environmental causes of pulmonary fibrosis.Secreted and membrane-bound mucins and idiopathic peptic ulcer disease.Mucins and pancreatic cancer.Loss of MUC2 expression predicts disease recurrence and poor outcome in colorectal carcinoma.Idiopathic Pulmonary Fibrosis: A Genetic Disease That Involves Mucociliary Dysfunction of the Peripheral Airways.MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer.Establishment and characterization of novel gastric signet-ring cell and non signet-ring cell poorly differentiated adenocarcinoma cell lines with low and high malignant potential.GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin.Differential expression of mucins in Middle Eastern patients with colorectal cancer.Expression of MUC5AC, an early marker of pancreatobiliary cancer, is regulated by DNA methylation in the distal promoter region in cancer cells.The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection.Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth.Helicobacter pylori urease and flagellin alter mucin gene expression in human gastric cancer cells.
P2860
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P2860
Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Epigenetic regulation (DNA met ...... 6) in epithelial cancer cells.
@en
Epigenetic regulation (DNA met ...... 6) in epithelial cancer cells.
@nl
type
label
Epigenetic regulation (DNA met ...... 6) in epithelial cancer cells.
@en
Epigenetic regulation (DNA met ...... 6) in epithelial cancer cells.
@nl
prefLabel
Epigenetic regulation (DNA met ...... 6) in epithelial cancer cells.
@en
Epigenetic regulation (DNA met ...... 6) in epithelial cancer cells.
@nl
P2093
P2860
P50
P356
P1433
P1476
Epigenetic regulation (DNA met ...... C6) in epithelial cancer cells
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210479
P407
P577
2007-04-30T00:00:00Z