Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).
about
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid.Current Insights into Molecular Mechanisms of Alzheimer Disease and Their Implications for Therapeutic ApproachesVitamin A and Alzheimer's diseaseCerebrospinal fluid biomarkers of Alzheimer’s diseaseMolecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXVIdentification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE))Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid depositsInteraction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer diseaseCLAC binds to amyloid beta peptides through the positively charged amino acid cluster within the collagenous domain 1 and inhibits formation of amyloid fibrilsDecreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretasePresenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formationThe presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residueDissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's diseaseSoluble oligomers of the amyloid beta-protein impair synaptic plasticity and behaviorProtein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseasesAmyloid beta-protein monomer folding: free-energy surfaces reveal alloform-specific differencesLoss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer diseaseCerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's diseasePassive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhageSimilar promotion of Abeta1-42 fibrillogenesis by native apolipoprotein E epsilon3 and epsilon4 isoformsA systematic review and meta-analysis of plasma amyloid 1-42 and tau as biomarkers for Alzheimer's diseaseThe roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer diseaseQuantitative detection of amyloid-β peptides by mass spectrometry: state of the art and clinical applicationsThe genetics and neuropathology of Alzheimer's diseaseAlzheimer's disease--a panorama glimpseWireless-electrodeless quartz-crystal-microbalance biosensors for studying interactions among biomolecules: a review.Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain TissueAPP processing in Alzheimer's diseaseNeuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?The Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer´s DiseaseDense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentricProteolytic processing of Alzheimer's β-amyloid precursor proteinPen-2 is incorporated into the gamma-secretase complex through binding to transmembrane domain 4 of presenilin 1Morphological changes of the human purkinje cells and deposition of neuritic plaques and neurofibrillary tangles on the cerebellar cortex of Alzheimer's diseaseThe fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brainsAccumulation of amyloid beta-protein in the low-density membrane domain accurately reflects the extent of beta-amyloid deposition in the brainA structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMRMultiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrils
P2860
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P2860
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Visualization of A beta 42
@nl
Visualization of A beta 42(43) ...... ited species is A beta 42(43).
@en
type
label
Visualization of A beta 42
@nl
Visualization of A beta 42(43) ...... ited species is A beta 42(43).
@en
prefLabel
Visualization of A beta 42
@nl
Visualization of A beta 42(43) ...... ited species is A beta 42(43).
@en
P2093
P1433
P1476
Visualization of A beta 42(43) ...... ited species is A beta 42(43).
@en
P2093
P356
10.1016/0896-6273(94)90458-8
P407
P577
1994-07-01T00:00:00Z