Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1.
about
Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis.MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib.Development of venetoclax for therapy of lymphoid malignancies.Bone marrow microenvironment-derived signals induce Mcl-1 dependence in multiple myeloma.Targeting BCL2 With BH3 Mimetics: Basic Science and Clinical Application of Venetoclax in Chronic Lymphocytic Leukemia and Related B Cell MalignanciesIn Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma.Increased expression of the tight junction protein TJP1/ZO-1 is associated with upregulation of TAZ-TEAD activity and an adult tissue stem cell signature in carfilzomib-resistant multiple myeloma cells and high-risk multiple myeloma patients.Current strategies for salvage treatment for relapsed classical Hodgkin lymphoma.The life and death of immune cell types: the role of BCL-2 anti-apoptotic molecules.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo.The BCL-2 arbiters of apoptosis and their growing role as cancer targets.Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells.Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer.LncRNA NEAT1 promotes dexamethasone resistance in multiple myeloma by targeting miR-193a/MCL1 pathway.Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma.Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.Pathways and mechanisms of venetoclax resistance.PGC1β regulates multiple myeloma tumor growth through LDHA-mediated glycolytic metabolism
P2860
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P2860
Hierarchy for targeting prosurvival BCL2 family proteins in multiple myeloma: pivotal role of MCL1.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@en
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@nl
type
label
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@en
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@nl
prefLabel
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@en
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@nl
P2093
P50
P1433
P1476
Hierarchy for targeting prosur ...... myeloma: pivotal role of MCL1.
@en
P2093
Andrew Spencer
Chris D Riffkin
Jean-Marc Garnier
Seong Lin Khaw
Tiffany Khong
P304
P356
10.1182/BLOOD-2016-03-704908
P407
P577
2016-07-27T00:00:00Z