Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway.

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Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway.High glucose suppresses the viability and proliferation of HTR‑8/SVneo cells through regulation of the miR‑137/PRKAA1/IL‑6 axis.

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Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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type

Item

label

Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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prefLabel

Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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Triptolide prevents extracellu ...... g microRNA-137/Notch1 pathway.

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Baocheng Chang

http://www.w3.org/2001/XMLSchema#string

Chunjun Li

http://www.w3.org/2001/XMLSchema#string

Fei Han

http://www.w3.org/2001/XMLSchema#string

Juhong Yang

http://www.w3.org/2001/XMLSchema#string

Liming Chen

http://www.w3.org/2001/XMLSchema#string

Shanshan Wang

http://www.w3.org/2001/XMLSchema#string

Yunpeng Chang

http://www.w3.org/2001/XMLSchema#string

Zhe Han

http://www.w3.org/2001/XMLSchema#string

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MicroRNAs: genomics, biogenesis, mechanism, and function

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.

Modulation of notch-1 signaling alleviates vascular endothelial growth factor-mediated diabetic nephropathy.

NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model.

Extracellular matrix metabolism in diabetic nephropathy.

Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts.

Structural-functional relationships in diabetic nephropathy.

Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation.

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets.

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

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2225-2237

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scholarly article

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10.1002/JCP.26092

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233

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Bei Sun

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2017-07-11T00:00:00Z

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28695984

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P921

microRNA

Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway.

about

P2860

P2860

Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway.

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