Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS. - Wikidata - awgldk - TriplyDB

Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS.

Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS.

http://www.wikidata.org/entity/Q48151677

about

X MARCKS the spot: myristoylated alanine-rich C kinase substrate in neuronal function and disease Prion protein accumulation in lipid rafts of mouse aging brain Screening assay for small-molecule inhibitors of synaptojanin 1, a synaptic phosphoinositide phosphatase.Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP2) roles for synaptic plasticity using chemically induced dimerization Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents.Cholesterol in brain disease: sometimes determinant and frequently implicated.Phospho-regulated Drosophila adducin is a determinant of synaptic plasticity in a complex with Dlg and PIP2 at the larval neuromuscular junction.MicroRNA-572 improves early post-operative cognitive dysfunction by down-regulating neural cell adhesion molecule 1.The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization.MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging.The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory.Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation.Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophrenia Lipid dynamics at dendritic spines.Protein Kinase C Activation as a Potential Therapeutic Strategy in Alzheimer's Disease: Is there a Role for Embryonic Lethal Abnormal Vision-like Proteins?Calpains: Master Regulators of Synaptic Plasticity.Distinct Properties of Long-Term Potentiation in the Dentate Gyrus along the Dorsoventral Axis: Influence of Age and Inhibition.Insights into the inhibitory mechanism of triazole-based small molecules on phosphatidylinositol-4,5-bisphosphate binding pleckstrin homology domain.Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior.MARCKS and MARCKS-like proteins in development and regeneration.Metabotropic Acetylcholine and Glutamate Receptors Mediate PI(4,5)P Depletion and Oscillations in Hippocampal CA1 Pyramidal Neurons in situ MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network

P2860

Q26777270-F07188E4-24F1-48A7-85A6-5A628B43DD42 Q27306972-1944B05E-B664-4991-8678-0126F953FF31 Q33561690-7EC3E880-9529-45BA-B674-ADC5D8C55C1A Q33794187-093C1B90-A205-433D-BE1E-B996FD222A03 Q33991462-239FD878-8F86-41D2-A848-A0BA14B448D2 Q34621446-3D43EE2B-3396-4220-A925-C353C8BBFD47 Q34698720-C727AF9C-0D30-4867-B07C-9CBF0D44B810 Q35101632-7D8B5E9E-6F39-4F73-85E7-CE023C98513C Q35808898-D36F106A-6E41-4EF2-B46B-5C23EDA048CD Q36057629-F1D05D4A-4FAD-4FFB-B702-C42803C44685 Q36664851-403F0B10-AB6E-40C7-9BA7-0CEC7F7DDFF9 Q36835981-6EEADA5B-93D9-4780-9A41-6C3A159FA75B Q37723680-03B6737E-874E-4D00-9174-710C7FDE37E2 Q38242813-81463990-F8E7-4DE4-B4CE-336549A169BD Q38784086-CB530BCA-D974-4DD1-94CF-4D2E6F5C4ACD Q38836512-A2DCA4F9-7C56-4C4A-9F63-48343FEAABE5 Q40986217-3F16783A-63AB-4ECF-8DA9-1A24FA02E338 Q46351354-4CE6196D-D9E6-420B-92E6-F5D942FAE792 Q47981611-D81E664A-7243-4DA2-B0B7-CFD1650FFE60 Q54978517-B516DF5D-81D7-4929-BE6D-AF3CC59BA5AA Q58699685-0B6737C1-7568-4A02-A1C2-50DE7AA26694 Q58763383-F58E6DC0-D763-41E5-A7A7-CA2304BE4EFE

P2860

Low hippocampal PI(4,5)P₂ contributes to reduced cognition in old mice as a result of loss of MARCKS.

http://www.wikidata.org/entity/Q48151677

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年学术文章

@wuu

2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

2013年學術文章

@zh

2013年學術文章

@zh-hant

name

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@en

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@nl

type

label

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@en

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@nl

prefLabel

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@en

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@nl

P1433

Q48151677-934E013B-0875-4011-823E-728525009189

P1476

Q48151677-66D916FC-B4DF-48D8-B5A7-CA0C002AF2AB

P2093

Q48151677-0D761DDD-2BA7-40E6-841C-61464E8FCAC7

Q48151677-236820FA-FFDE-430D-92CD-594A7FCFBEF3

Q48151677-25ADF325-0BF0-43ED-A1EF-5433C4C6DFB4

Q48151677-3AF7E37D-2D95-4905-AEEF-6DDBCC782ACA

Q48151677-5808878E-7B87-4127-8AEC-8281B3214165

Q48151677-6C3C716E-4C77-4EF7-B5E7-63C4B5751D00

Q48151677-A9248907-B657-4F5A-92C5-927B3C3617B2

Q48151677-EAB1B790-10B3-4962-8CA3-8272B4D7D189

Q48151677-FB4D057F-C6A5-4AA3-8352-0A01B954D1CC

P2860

Q48151677-047E9A8A-85A9-47CF-831B-036AB57DDC02

Q48151677-0BBCF465-46C8-402B-A059-6CB21CF3C274

Q48151677-0E44E1D9-F9BF-40F4-8364-0B3659933B32

Q48151677-17CCCED5-A53B-45A8-A0E9-7326FD003CFE

Q48151677-1A4CE3E6-6F9D-42B3-9995-2E9745219BEB

Q48151677-21E22857-DBEA-4CF8-926C-82617B4CBDFA

Q48151677-26D2DC9C-A5A6-4AB5-834E-D8FC1C815940

Q48151677-2FD0AA50-3A03-4889-89CF-91244ED56F40

Q48151677-3135D115-0802-4B00-8C74-32F3E40FEEB3

Q48151677-39DDB6DF-B5FF-45B8-9EE6-1CFE3CBDF0D6

P2888

Q48151677-58FBF192-6635-4443-9EE6-DCF370C1EA00

P304

Q48151677-C36CD2CE-1B1A-4D24-B0CC-C9F833BC825E

P31

Q48151677-15AC0273-4940-4099-B9A6-786ACD4ECC45

P356

Q48151677-6A41DE33-E446-4639-B0D8-0593785D78E5

P407

Q48151677-EF776A9A-F58F-44CB-B295-7B74F021C190

P433

Q48151677-C0958692-80F4-4F4E-B445-C8DC176F44B2

P478

Q48151677-4B9EA1CC-0A32-4D4A-8A36-5F085DE2DC30

P50

Q48151677-650AC0C0-EB26-48BE-B400-FF06D161FF66

P577

Q48151677-82A12F08-32E4-4A12-A60F-97130E33ECD5

P5875

Q48151677-9FD83BE9-AE6E-4383-B7AE-1BD45D1721DB

P698

Q48151677-F94F2510-D235-40FC-809B-415991B8B4FD

P356

P1433

Nature Neuroscience

P1476

Low hippocampal PI(4,5)P₂ cont ...... as a result of loss of MARCKS.

@en

P2093

Andrea Buzzi

http://www.w3.org/2001/XMLSchema#string

Carlos G Dotti

http://www.w3.org/2001/XMLSchema#string

Detlef Balschun

http://www.w3.org/2001/XMLSchema#string

Laura Trovò

http://www.w3.org/2001/XMLSchema#string

Marinee Chuah

http://www.w3.org/2001/XMLSchema#string

Rudi D'Hooge

http://www.w3.org/2001/XMLSchema#string

Tariq Ahmed

http://www.w3.org/2001/XMLSchema#string

Thierry Vandendriessche

http://www.w3.org/2001/XMLSchema#string

Zsuzsanna Callaerts-Vegh

http://www.w3.org/2001/XMLSchema#string

P2860

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1

Regulation of postsynaptic AMPA responses by synaptojanin 1

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

Phosphoinositides in cell regulation and membrane dynamics

Regulation of phosphoinositide-specific phospholipase C

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

Essential role for the PKC target MARCKS in maintaining dendritic spine morphology

Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior

P2888

P304

449-455

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NN.3342

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-02-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

235716353

http://www.w3.org/2001/XMLSchema#string

P698

23434911

http://www.w3.org/2001/XMLSchema#string