The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
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Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia.Whole-genome sequencing of spermatocytic tumors provides insights into the mutational processes operating in the male germline.Whole-exome sequencing of a rare case of familial childhood acute lymphoblastic leukemia reveals putative predisposing mutations in Fanconi anemia genesGenome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome.Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2.Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemiaGenetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.The role of the RAS pathway in iAMP21-ALL.Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues.CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response.High hyperdiploid acute lymphoblastic leukemia (ALL)-A 25-year population-based survey of the Austrian ALL-BFM (Berlin-Frankfurt-Münster) Study Group.In silico frameworks for systematic pre-clinical screening of potential anti-leukemia therapeutics.Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics.Genetic Basis of Acute Lymphoblastic Leukemia.The genetic landscape of paediatric de novo acute myeloid leukaemia as defined by single nucleotide polymorphism array and exon sequencing of 100 candidate genes.High hyperdiploid childhood acute lymphoblastic leukemia: Chromosomal gains as the main driver event.Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots.Chromosome gains drive childhood ALL.Suppressors and activators of JAK-STAT signaling at diagnosis and relapse of acute lymphoblastic leukemia in Down syndrome.A germ-line deletion of APOBEC3B does not contribute to subtype-specific childhood acute lymphoblastic leukemia etiology.Mutational Landscape of Pediatric Acute Lymphoblastic Leukemia.TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia.Blastic transformation of juvenile myelomonocytic leukemia caused by the copy number gain of oncogenic KRAS.New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update.Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.Abnormally high expression of POLD1, MCM2, and PLK4 promotes relapse of acute lymphoblastic leukemia.Genetics and epigenetics of pediatric leukemia in the era of precision medicineNew biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia
P2860
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P2860
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@en
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@nl
type
label
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@en
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@nl
prefLabel
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@en
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@nl
P2093
P2860
P50
P356
P1433
P1476
The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
@en
P2093
Anders Castor
Andrea Biloglav
Bertil Johansson
Gisela Barbany
Helene Sjögren
Linda Fogelstrand
Linda Olsson
Marianne Rissler
P2860
P2888
P304
P356
10.1038/NG.3301
P407
P577
2015-05-11T00:00:00Z