Differential sulfations and epimerization define heparan sulfate specificity in nervous system development.
about
Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadismA molecular mechanism for the heparan sulfate dependence of slit-robo signalingStructure and functional relevance of the Slit2 homodimerization domainGene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2D-glucuronyl C5-epimerase acts in dorso-ventral axis formation in zebrafishHeparan sulfate proteoglycans: a sugar code for vertebrate development?The Caenorhabditis elegans epidermis as a model skin. II: differentiation and physiological rolesA network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegansTransmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels.Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesisFunctional Requirements for Heparan Sulfate Biosynthesis in Morphogenesis and Nervous System Development in C. elegansMice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethalityPanels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activityChondroitin-4-sulfation negatively regulates axonal guidance and growthHeparan sulfate 2-O-sulfotransferase is required for triglyceride-rich lipoprotein clearanceMolecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase.Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans.Matrix regulators in neural stem cell functions.Combinatorial roles of heparan sulfate proteoglycans and heparan sulfates in Caenorhabditis elegans neural development.Syndecan promotes axon regeneration by stabilizing growth cone migration.Two Golgi-resident 3'-Phosphoadenosine 5'-phosphosulfate transporters play distinct roles in heparan sulfate modifications and embryonic and larval development in Caenorhabditis elegans.Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegansThe specificity of interactions between proteins and sulfated polysaccharides.Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones.Mutational study of heparan sulfate 2-O-sulfotransferase and chondroitin sulfate 2-O-sulfotransferase.Genetic analysis of the heparan modification network in Caenorhabditis elegansHeparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells.2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.Defects in eye development in transgenic mice overexpressing the heparan sulfate proteoglycan agrin.Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant gliomaLAR receptor tyrosine phosphatases and HSPGs guide peripheral sensory axons to the skinGpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice.SDN-1/Syndecan Acts in Parallel to the Transmembrane Molecule MIG-13 to Promote Anterior Neuroblast Migration.When sugars guide axons: insights from heparan sulphate proteoglycan mutants.Novel therapeutic targets in the brain tumor microenvironmentSugar codes for axons?Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling.The TCF4/β-catenin pathway and chromatin structure cooperate to regulate D-glucuronyl C5-epimerase expression in breast cancer.Heparan sulphate proteoglycans: the sweet side of development.The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans
P2860
Q24307650-3D101908-53CC-4F52-AB22-37A6CD66BFB3Q24308849-02ED7A2B-CAC0-4AF3-8A2C-151D30509054Q24317365-DBE246A7-2B77-400C-BF9C-4F0DC1CB6ADCQ24673634-BF816694-C9E4-47A8-B26A-DEEF55E3D9CFQ24816968-E685677F-9994-4EFF-A8D0-33C5A14A47E7Q26781120-67373526-2A3C-4E4A-97DB-A678A0D37571Q27000795-DD07E4EC-CF03-455B-BB08-10AA51DB80CDQ27306247-FD9F02EC-F678-4014-AD35-7C96AA15505FQ27310200-7D40FB0F-15ED-4024-B731-321F624CB459Q27652967-54EAD36D-0F25-458B-B415-081FE4C97C55Q28469504-9F63966F-85A1-4D7E-89AD-E211DED362D3Q28592475-81AABA76-4AD7-404B-B63D-C4919ED03BB6Q28822558-97FA4249-FFC2-41A0-810B-F1A0E6285BABQ30483928-7F6D58AB-271F-4B1F-BFD9-56C1DDA0BE1EQ33581252-1BF3BC1C-FB4F-4DED-BD22-965441053F33Q33676686-06B6CB41-1661-49BD-BD16-B0CB92A6DE43Q33817351-C4815323-4E7D-4644-BC86-24A1B4877891Q33819268-7B3D3807-6C0A-4409-93F1-7EE027DB1F5BQ33940136-00F898C4-5433-43F1-8E1C-DDE78042FBD6Q34022245-C6859571-B59D-45A2-8DE9-22B46D30FCFDQ34042679-D676CB2C-3123-4A81-A053-2ECBD280D257Q34242931-3AD1F755-45BC-4C97-9602-F64670085AF1Q34474956-C89B8F8A-28FD-491B-B1FB-319691B967A8Q34486134-44844EDE-B6C9-4DF9-A704-16A26199377AQ34602695-B76107AD-2FDF-40F6-8E76-563671BE68A6Q34947657-03ECE0DA-169C-4511-A2FF-AEE8AAC6AE7FQ35221235-ED27BA56-CBEB-4DB0-84C9-2EE7029CECA6Q35663605-4884BC13-400B-42F9-BCCC-D069BE5B297DQ35697330-3BD7B398-3A55-4F5F-9144-EBAC5EBF3AD1Q35780214-7600D08E-2656-4541-8BD5-AD55CA03B567Q35818854-AE1AE002-C2AE-4426-9420-5F13E7A5712FQ35821158-914A2C29-488C-4F55-9A86-3175DFDF9FFEQ35926373-0CD02B91-3F46-428C-87C3-71BF24EAC32BQ35968447-4FD11C2C-F360-4D9A-89F7-B7BBBDBA425FQ36071884-34197416-DA98-46ED-8603-B26B90FAEFEBQ36105212-B62B8BD4-FF43-4587-B42F-CDF555C9642DQ36118561-1609904C-B27B-426C-8AEC-04DA0EC7C78BQ36187860-1B150A22-8679-4A9A-A8BE-BFD4C4E6B712Q36216124-3BC33937-C474-4772-AB35-3DD58F00757BQ36257348-BC5A9601-F1BB-42A9-9D79-16460EFD9979
P2860
Differential sulfations and epimerization define heparan sulfate specificity in nervous system development.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Differential sulfations and ep ...... in nervous system development.
@en
Differential sulfations and ep ...... in nervous system development.
@nl
type
label
Differential sulfations and ep ...... in nervous system development.
@en
Differential sulfations and ep ...... in nervous system development.
@nl
prefLabel
Differential sulfations and ep ...... in nervous system development.
@en
Differential sulfations and ep ...... in nervous system development.
@nl
P1433
P1476
Differential sulfations and ep ...... in nervous system development.
@en
P2093
Hannes E Bülow
P304
P356
10.1016/S0896-6273(04)00084-4
P407
P577
2004-03-01T00:00:00Z