A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.
about
The lipid phosphatase activity of PTEN is critical for its tumor supressor functionPHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segmentsA natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxisPTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells mediated by p27kip1UV induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal C1 41 cells through hydrogen peroxideAKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomasKinetic mechanism of AKT/PKB enzyme familyInsulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinaseKank regulates RhoA-dependent formation of actin stress fibers and cell migration via 14-3-3 in PI3K-Akt signalingRak functions as a tumor suppressor by regulating PTEN protein stability and functionAH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulationLiver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activityInhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through AktConvergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription.Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating AktAmplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNATrypanosoma cruzi targets Akt in host cells as an intracellular antiapoptotic strategyMammalian expression of infrared fluorescent proteins engineered from a bacterial phytochromeAKT/PKB signaling: navigating downstreamTcl1 enhances Akt kinase activity and mediates its nuclear translocationExpression of CX3CR1 chemokine receptors on neurons and their role in neuronal survivalSolenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesisDeficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic miceRegulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NF-kappaB/IkappaB pathwayAkt isoforms in vascular diseasePosttranslational regulation of Akt in human cancerAkt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progressionPhosphatidylinositol 3-kinase mutations identified in human cancer are oncogenicThe critical role of Akt in cardiovascular functionp38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophilsConservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domainsInhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial CellsArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survivalCharacterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serumOncogenic mutations of PIK3CA in human cancersDownregulation of Akt1 inhibits anchorage-independent cell growth and induces apoptosis in cancer cellsPI3K/PTEN signaling in angiogenesis and tumorigenesis
P2860
Q22007981-DCA4D9B7-4F2C-4E35-BB62-64E4695E0934Q22010881-8459E228-289E-4277-AA1C-9518773CE0C7Q22253346-6F734492-D42F-46E6-9DA2-2C4F8ED812BEQ22254699-316892DA-86BB-48F3-82FF-F52D49F8335DQ23911187-B81583A7-2A5D-42A7-811F-55061B7DF80BQ24294176-E2BA665D-2F6A-4254-A1C8-4CF9DCC73D1EQ24307898-876C081F-BDD1-46D9-9C8B-19E02EDB324AQ24309311-3045576E-7D07-4E5D-A607-96EBBECD9408Q24310007-A99A0EBC-A9C5-4CC2-A97B-C222C0E003D9Q24312999-ECF35EF1-5E9C-43DF-B5EA-28D6A839722CQ24317438-9B73C464-C156-43F7-9C3D-AA1B2C8B0AB5Q24337815-733662C9-D02E-41D6-8126-3E465518BA0FQ24514761-49D0C456-E4E0-45E0-B0AC-89DC283F8A15Q24533977-7BC781F2-2C97-43D9-99E2-CBCBB0336BB9Q24537174-3BB183A4-1349-47F0-A58A-839797FFB575Q24537733-BE98CDFE-9FB1-484E-9BF0-B6B997AFE05FQ24551018-9F13DC15-0E44-496E-8FC2-B8D5AF4ACAC1Q24564005-4F69CBC6-FD1C-4065-A71C-03F521430902Q24568308-280D41B9-AA48-4224-B765-1A75603ED968Q24594768-C6E0D743-2CBF-4E86-AFDC-D1C10B8F7302Q24652377-50051EEA-7436-403C-A8A4-11C7737BCC6EQ24657857-04ECC6EF-E374-4733-BE71-EE75B262D90CQ24670140-F89076B9-A0D7-4C26-B188-147D633B3952Q24676224-FDCA632F-86A7-474C-8914-980171DAE0BBQ24681382-7B8DF9DD-C6B7-437F-880B-2A3888345683Q24796025-09818E83-1E0B-4FF3-9CF3-4F99CEB82A2CQ24806402-26FA16B6-A8C6-42A4-A566-8FD5C3DCE2B1Q26851565-4B1947C5-C644-4019-A4F6-1DD2FF0C6784Q27027815-08F64A28-3040-4C17-9E63-95B8522BA2CBQ27339328-6A8DCCA0-A3CF-48B5-B279-52D297BCAD52Q27824826-EC5D029E-33CB-4DFE-B81F-B00A14BA454AQ28083829-E0051841-2176-4B2C-8D55-9AAEBF72ED1EQ28141837-B616F34B-72A5-493D-98BB-8AADEC2F1A6CQ28187467-EF27E9F2-80EE-4721-87B5-CDDA71B808F1Q28202566-06A00A53-8336-492A-B6BE-8B59C03B90A9Q28241283-F77AD0B4-BC53-4F1E-8FEC-96F0C3885365Q28267355-31A46182-54BC-4959-8905-688AA43C8C9BQ28284802-28B8F647-097A-4437-AF82-6B42EDB81403Q28360348-4C91A5DF-50B5-4E04-980F-B11881DD294BQ28383083-5863652C-4F6B-4780-A770-85D9D4CC193F
P2860
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh-hant
name
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@en
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@nl
type
label
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@en
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@nl
prefLabel
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@en
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@nl
P2093
P356
P1433
P1476
A retroviral oncogene, akt, en ...... containing an SH2-like region.
@en
P2093
P304
P356
10.1126/SCIENCE.1833819
P407
P577
1991-10-01T00:00:00Z