The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
about
Recent advances in understanding transcription termination by RNA polymerase IIRrp6: Integrated roles in nuclear RNA metabolism and transcription terminationFail-safe transcription termination: Because one is never enoughTranscriptional termination in mammals: Stopping the RNA polymerase II juggernautRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeChromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity.DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts.Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis.Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing.Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeastThe Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection.Transcription termination and the control of the transcriptome: why, where and how to stop.Transcriptional reprogramming in cellular quiescence.Effects of Transcription Elongation Rate and Xrn2 Exonuclease Activity on RNA Polymerase II Termination Suggest Widespread Kinetic Competition.Genome stability versus transcript diversity.Lingering Questions about Enhancer RNA and Enhancer Transcription-Coupled Genomic Instability.Pause & go: from the discovery of RNA polymerase pausing to its functional implications.Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough.TINTIN, at the interface of chromatin, transcription elongation, and mRNA processing.Transcription pausing: biological significance of thermal fluctuations biased by repetitive genomic sequences.Intragenic Enhancers Attenuate Host Gene Expression.Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export.Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity.A long noncoding (lnc) RNA governs expression of the phosphate transporter Pho84 in fission yeast and has cascading effects on the flanking prt lncRNA and pho1 genes.Surveillance-ready transcription: nuclear RNA decay as a default fate.Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeastCondensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcriptionLong noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast
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The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
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2014 nî lūn-bûn
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The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@en
The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@nl
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label
The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@en
The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@nl
prefLabel
The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@en
The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@nl
P2093
P2860
P356
P1476
The RNA exosome promotes transcription termination of backtracked RNA polymerase II.
@en
P2093
François Bachand
Marc Larochelle
Samuel Marguerat
Sophie Atkinson
P2860
P2888
P304
P356
10.1038/NSMB.2893
P577
2014-09-21T00:00:00Z