Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia.
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Mechanisms of neuregulin actionMouse Genetic Models of Human Brain DisordersNeuropathologic implication of peripheral neuregulin-1 and EGF signals in dopaminergic dysfunction and behavioral deficits relevant to schizophrenia: their target cells and time windowPhenotypic characterization of transgenic mice overexpressing neuregulin-1Gene × Environment Interactions in Schizophrenia: Evidence from Genetic Mouse ModelsNeuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathwayThe involvement of Type II Neuregulin-1 in rat visuospatial learning and memoryDisruption of the neuregulin 1 gene in the rat alters HPA axis activity and behavioral responses to environmental stimuliType III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit componentsNeuregulin 1 Prevents Phencyclidine-Induced Behavioral Impairments and Disruptions to GABAergic Signaling in MiceFirst Behavioural Characterisation of a Knockout Mouse Model for the Transforming Growth Factor (TGF)-β Superfamily Cytokine, MIC-1/GDF15Partial genetic deletion of neuregulin 1 modulates the effects of stress on sensorimotor gating, dendritic morphology, and HPA axis activity in adolescent mice.Positive allosteric modulation of GABAB receptors ameliorates sensorimotor gating in rodent models.Neurodevelopmental animal models of schizophrenia: role in novel drug discovery and developmentSchizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models.Comprehensive behavioural analysis of Long Evans and Sprague-Dawley rats reveals differential effects of housing conditions on tests relevant to neuropsychiatric disorders.Interaction of genotype and environment: effect of strain and housing conditions on cognitive behavior in rodent models of schizophrenia.Role of Abca7 in mouse behaviours relevant to neurodegenerative diseases.Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice.Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice.Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspectsPrepulse inhibition and genetic mouse models of schizophrenia.Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions.Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficitsInhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models.Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillationAvoiding mouse traps in schizophrenia genetics: lessons and promises from current and emerging mouse models.Partial genetic deletion of neuregulin 1 and adolescent stress interact to alter NMDA receptor binding in the medial prefrontal cortex.mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.Gene expression profiling in rodent models for schizophrenia.Neuregulin 1 expression and electrophysiological abnormalities in the Neuregulin 1 transmembrane domain heterozygous mutant mouseTransgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation.White matter abnormalities and animal models examining a putative role of altered white matter in schizophrenia.The interaction of disrupted type II neuregulin 1 and chronic adolescent stress on adult anxiety- and fear-related behaviors.What does a mouse tell us about neuregulin 1-cannabis interactions?Novel molecular changes induced by Nrg1 hypomorphism and Nrg1-cannabinoid interaction in adolescence: a hippocampal proteomic study in miceNeuregulin 1: a prime candidate for research into gene-environment interactions in schizophrenia? Insights from genetic rodent models.Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copperDecanalization mediating gene-environment interactions in schizophrenia and other psychiatric disorders with neurodevelopmental etiology.Can the role of genetic factors in schizophrenia be enlightened by studies of candidate gene mutant mice behaviour?
P2860
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P2860
Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Altered motor activity, explor ...... r understanding schizophrenia.
@en
Altered motor activity, explor ...... r understanding schizophrenia.
@nl
type
label
Altered motor activity, explor ...... r understanding schizophrenia.
@en
Altered motor activity, explor ...... r understanding schizophrenia.
@nl
prefLabel
Altered motor activity, explor ...... r understanding schizophrenia.
@en
Altered motor activity, explor ...... r understanding schizophrenia.
@nl
P2860
P50
P1476
Altered motor activity, explor ...... or understanding schizophrenia
@en
P2093
P2860
P304
P356
10.1111/J.1601-183X.2006.00298.X
P407
P577
2007-02-13T00:00:00Z