Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.
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Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix componentsThe product of the EMS1 gene, amplified and overexpressed in human carcinomas, is homologous to a v-src substrate and is located in cell-substratum contact sitesIdentification of three additional genes contiguous to the glucocerebrosidase locus on chromosome 1q21: implications for Gaucher diseaseDegenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surfaceMUC1 (EMA) is preferentially expressed by ALK positive anaplastic large cell lymphoma, in the normally glycosylated or only partly hypoglycosylated formMUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA.Expression of mucin genes in the human testis and its relationship to spermatogenesis.Current status of mucins in the diagnosis and therapy of cancer.MUC1: a multifaceted oncoprotein with a key role in cancer progression.The gastrointestinal mucus system in health and diseaseCharacterization of porcine intestinal receptors for the K88ac fimbrial adhesin of Escherichia coli as mucin-type sialoglycoproteins.MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): a multivariate analysis.Serum sialyl Lewis X-i antigen in lung adenocarcinoma and idiopathic pulmonary fibrosisProduction of anti-breast cancer monoclonal antibodies using a glutathione-S-transferase-MUC1 bacterial fusion protein.Characterization of cis-acting elements regulating transcription of the human DF3 breast carcinoma-associated antigen (MUC1) gene.Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients.Effects of molecular structural variants on serum Krebs von den Lungen-6 levels in sarcoidosis.Molecular cloning and sequencing of a canine tracheobronchial mucin cDNA containing a cysteine-rich domain.Suggestive evidence for two different mucin genes in rat intestineCloning and analysis of human gastric mucin cDNA reveals two types of conserved cysteine-rich domains.Genetic regulation of MUC1 alternative splicing in human tissuesMucins and pancreatic cancer.Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteinsSputum mucin 1 is increased during the acute phase of chronic obstructive pulmonary disease exacerbation.Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer.MUC1/A and MUC1/B splice variants differentially regulate inflammatory cytokine expressionA mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphismA single nucleotide polymorphism in an exon dictates allele dependent differential splicing of episialin mRNA.The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylationDifferential mucin gene expression in human pancreatic and colon cancer cells.Distinct populations of high-M(r) mucins secreted by different human salivary glands discriminated by density-gradient electrophoresis.Topographical investigations of human ovarian-carcinoma polymorphic epithelial mucin by scanning tunnelling microscopyStructural features of the low-molecular-mass human salivary mucin.MUC2 is the prominent colonic mucin expressed in ulcerative colitis.A Mucin1 C-terminal Subunit-directed Monoclonal Antibody Targets Overexpressed Mucin1 in Breast Cancer.Effect of MUC1 mucin, an anti-adhesion molecule, on tumor cell growth.Increased expression after X-irradiation of MUC1 in cultured human colon carcinoma HT-29 cells.Characterization of OM-B monoclonal antibody-defined antigen associated with mucinous type human ovarian tumor.
P2860
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P2860
Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.
description
1990 nî lūn-bûn
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name
Episialin, a carcinoma-associa ...... ith alternative amino termini.
@en
Episialin, a carcinoma-associa ...... ith alternative amino termini.
@nl
type
label
Episialin, a carcinoma-associa ...... ith alternative amino termini.
@en
Episialin, a carcinoma-associa ...... ith alternative amino termini.
@nl
prefLabel
Episialin, a carcinoma-associa ...... ith alternative amino termini.
@en
Episialin, a carcinoma-associa ...... ith alternative amino termini.
@nl
P2093
P1476
Episialin, a carcinoma-associa ...... with alternative amino termini
@en
P2093
Gennissen AM
Ligtenberg MJ
P304
P407
P577
1990-04-01T00:00:00Z