Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.
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Prion hypothesis: the end of the controversy?Pseudoknots in prion protein mRNAs confirmed by comparative sequence analysis and pattern searchingSynthetic amyloid-beta oligomers impair long-term memory independently of cellular prion proteinSpontaneous generation of prion infectivity in fatal familial insomnia knockin miceProbing the role of PrP repeats in conformational conversion and amyloid assembly of chimeric yeast prionsDe novo generation of infectious prions in vitro produces a new disease phenotypeSpreading of a prion domain from cell-to-cell by vesicular transport in Caenorhabditis elegansFatal prion disease in a mouse model of genetic E200K Creutzfeldt-Jakob diseaseNMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural FeaturesThe toxicity of antiprion antibodies is mediated by the flexible tail of the prion proteinG-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeThe octarepeat region of the prion protein is conformationally altered in PrP(Sc)Transmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotypeExpression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunctionSUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3Mutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 SubunitEarly onset prion disease from octarepeat expansion correlates with copper binding propertiesDe novo generation of a transmissible spongiform encephalopathy by mouse transgenesisCytoplasmic prion protein induces forebrain neurotoxicityPrion protein insertional mutations increase aggregation propensity but not fiber stability.Molecular distinction between pathogenic and infectious properties of the prion protein.The comprehensive native interactome of a fully functional tagged prion proteinSpontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein.Immunopurification of pathological prion protein aggregatesEvolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease.Cellular biology of prion diseases.The intriguing prion disorders.Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.High-resolution structure of infectious prion protein: the final frontierCell type-specific neuroprotective activity of untranslocated prion protein.Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion proteinA highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal deathImmunodetection of disease-associated mutant PrP, which accelerates disease in GSS transgenic mice.Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteinsRole of plasminogen in propagation of scrapie.Mouse models for studying the formation and propagation of prions.Prion protein genes and prion diseases: studies in transgenic mice.Strain specific resistance to murine scrapie associated with a naturally occurring human prion protein polymorphism at residue 171.The N-terminal, polybasic region is critical for prion protein neuroprotective activity.Huntington disease phenocopy is a familial prion disease.
P2860
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P2860
Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Neurological illness in transg ...... with an insertional mutation.
@en
Neurological illness in transg ...... with an insertional mutation.
@nl
type
label
Neurological illness in transg ...... with an insertional mutation.
@en
Neurological illness in transg ...... with an insertional mutation.
@nl
prefLabel
Neurological illness in transg ...... with an insertional mutation.
@en
Neurological illness in transg ...... with an insertional mutation.
@nl
P1433
P1476
Neurological illness in transg ...... n with an insertional mutation
@en
P2093
P304
P356
10.1016/S0896-6273(00)80653-4
P407
P577
1998-12-01T00:00:00Z