Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
about
RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.Familial frontotemporal dementia-associated presenilin-1 c.548G>T mutation causes decreased mRNA expression and reduced presenilin function in knock-in mice.The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through.Generation and analysis of the thiazide-sensitive Na+ -Cl- cotransporter (Ncc/Slc12a3) Ser707X knockin mouse as a model of Gitelman syndrome.
P2860
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
@en
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
@nl
type
label
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
@en
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
@nl
prefLabel
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
@en
Knock-in mice reveal nonsense-mediated mRNA decay in the brain.
@nl
P2860
P356
P1433
P1476
Knock-in mice reveal nonsense-mediated mRNA decay in the brain
@en
P2093
Andrée Dierich
Brigitte L Kieffer
P2860
P356
10.1002/DVG.20263
P577
2007-01-01T00:00:00Z