Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.

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Overexpression of MYCT1 Inhibits Proliferation and Induces Apoptosis in Human Acute Myeloid Leukemia HL-60 and KG-1a Cells and

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Q57073789-B16A64DF-5348-4E36-B3C7-590B545B0E2B

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Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.

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http://www.wikidata.org/entity/Q48316021

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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name

Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

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Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

@nl

type

Item

label

Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

@en

Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

@nl

prefLabel

Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

@en

Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

@nl

P1476

Predicting effective pro-apopt ...... erative dynamic BH3 profiling.

@en

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Adam Graham

http://www.w3.org/2001/XMLSchema#string

Claire Seedhouse

http://www.w3.org/2001/XMLSchema#string

Liban Elmi

http://www.w3.org/2001/XMLSchema#string

Michael Hall

http://www.w3.org/2001/XMLSchema#string

Monica Pallis

http://www.w3.org/2001/XMLSchema#string

Nigel Russell

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P2860

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.

BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.

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e0190682

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scholarly article

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10.1371/JOURNAL.PONE.0190682

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English

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Martin Grundy

Thomas Jones

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2018-01-03T00:00:00Z

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29298347

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apoptotic process

leukemia

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5752038

http://www.w3.org/2001/XMLSchema#string

Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.

about

P2860

P2860

Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

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P50

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P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

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P698

P921

P932