Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.
about
Functional genomics in osteoarthritis: Past, present, and futureObesity genetics in mouse and human: back and forth, and back againTargets, models and challenges in osteoarthritis researchGenetic contribution to osteoarthritis development: current state of evidenceOsteoarthritis in the XXIst century: risk factors and behaviours that influence disease onset and progressionFunctional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular StudyToll-like receptors and their soluble forms differ in the knee and thumb basal osteoarthritic joints.Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.Importance of ALDH1A enzymes in determining human testicular retinoic acid concentrations.Expression analysis of the osteoarthritis genetic susceptibility locus mapping to an intron of the MCF2L gene and marked by the polymorphism rs11842874.The Rotterdam Study: 2016 objectives and design update.Methylation quantitative trait locus analysis of osteoarthritis links epigenetics with genetic riskHEALER: homomorphic computation of ExAct Logistic rEgRession for secure rare disease variants analysis in GWASA large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Correlation of the osteoarthritis susceptibility variants that map to chromosome 20q13 with an expression quantitative trait locus operating on NCOA3 and with functional variation at the polymorphism rs116855380.Use of next-generation DNA sequencing to analyze genetic variants in rheumatic disease.Implementation of Functional Genomics for Bench-to-Bedside Transition in Osteoarthritis.Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand.Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis.[EXPRESS] Single Nucleotide Polymorphism in the COL11A2 Gene Associated with Heat Pain Sensitivity in Knee OsteoarthritisMeta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.Genome-Wide Association Study of Radiographic Knee Osteoarthritis in North American Caucasians.Genetic Determinants of Radiographic Knee Osteoarthritis in African Americans.Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis.Genetic architecture: the shape of the genetic contribution to human traits and disease.Pathways to understanding the genomic aetiology of osteoarthritis.A novel variant in GLIS3 is associated with osteoarthritis.Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritisFunctional Characterization of the Osteoarthritis Genetic Risk Residing at ALDH1A2 Identifies rs12915901 as a Key Target Variant
P2860
Q26749633-47F7945F-C7F1-4815-B6B9-6CA64D1E20C4Q26782027-E919B28F-71AE-41B1-ADBC-169EA46E2223Q26850147-49E07AAF-316D-481A-AA42-9E27EC1492EFQ26852663-E3131990-8B46-43C4-A761-4F87652D5430Q26998603-F79C7EB6-EC57-4702-AF74-E2263DB41DD6Q28596544-2B424E3F-6EBA-4BA4-B1C3-0A441802560FQ33697107-86C6CD93-DE6C-4030-95EE-4B9535430FD9Q33940184-2C4FEB01-1CBE-4EE8-B852-FB4255EA676EQ35014265-1FE2BC58-95F9-4B36-A0AC-8F1A55DC4AEBQ35846285-F44F5992-3DB2-46B6-85A5-35A1E6D9F06CQ36084114-F109C161-5C01-4C00-883A-8E2817471BFFQ36331594-4132F390-D45D-46FC-8F0D-26FFA836ACA9Q36538189-B2201CE7-DEFB-4314-870F-F831DE9ECC66Q36556369-707AABA8-ECE1-4E2C-91C2-ED07E42B99EEQ36799916-68A8CF8E-E92C-4185-92AD-3872ED6D87E1Q38383803-6437B993-17B2-4C6E-8087-1BED32399D95Q38538203-583FF6D5-80A6-4CF1-B6D8-FB8E3BF296B1Q38601744-AFEC31D2-8539-4937-B58E-9BC4B8C83451Q40425129-4ACB4B1D-B914-4350-BC89-831897450211Q41456236-2587DF42-8715-4B5A-A684-CE479BD2398DQ45807411-BDBDBF4F-D2C3-4BC1-8B09-8FD368B9236DQ46069031-404689E9-DD24-4DD1-A498-FEF558B81CCAQ46871499-242A508A-2FEC-43E0-95CD-73D97595D7A2Q47226678-A800F5FA-3271-4AF1-ACF9-A793900E96D8Q47579970-B54C4C56-0739-487C-9C2C-4A36C9A53024Q49608435-A4728B6E-CAD7-4278-BF17-FD7D64551E9BQ50048337-B5950C67-9F58-4E60-8D9C-038F79F48C81Q58695927-DA37ADA8-1573-4C45-8B17-22998C636E14Q58709893-157C87AA-26CC-43B5-BB74-AD48C0EACA3B
P2860
Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@en
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@nl
type
label
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@en
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@nl
prefLabel
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@en
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@nl
P2093
P2860
P50
P356
P1433
P1476
Severe osteoarthritis of the h ...... nd with rare variants at 1p31.
@en
P2093
Albert Hofman
Andre Uitterlinden
Annelieke M Strijbosch
Asgeir Sigurdsson
Aslaug Jonasdottir
Deborah Hart
Finnur F Eiriksson
Gisli Masson
Helgi Jonsson
Ingileif Jonsdottir
P2860
P2888
P304
P356
10.1038/NG.2957
P407
P50
P577
2014-04-13T00:00:00Z