Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
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D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptorControl of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-SerineN[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transportEvidence for functionally distinct synaptic NMDA receptors in ventromedial versus dorsolateral striatumSerine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmissionSSR504734 enhances basal expression of prepulse inhibition but exacerbates the disruption of prepulse inhibition by apomorphine.Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses.Modulation of sensorimotor gating in prepulse inhibition by conditional brain glycine transporter 1 deletion in miceBeyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.A critical role for glycine transporters in hyperexcitability disorders.Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine.The NMDA receptor as a target for cognitive enhancementEffects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related BehaviorWhy glycine transporters have different stoichiometries.Deletion of forebrain glycine transporter 1 enhances conditioned freezing to a reliable, but not an ambiguous, cue for threat in a conditioned freezing paradigm.Blockade of the N-Methyl-D-Aspartate Glutamate Receptor Ameliorates Lipopolysaccharide-Induced Renal Insufficiency.Inhibiting glycine transporter-1 facilitates cocaine-cue extinction and attenuates reacquisition of cocaine-seeking behavior.The N-methyl D-aspartate receptor glycine site and D-serine metabolism: an evolutionary perspectiveOxidative stress biomarkers in some rat brain structures and peripheral organs underwent cocaineFast synaptic inhibition in spinal sensory processing and pain control.Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity levelGlycine transporter-1 inhibition promotes striatal axon sprouting via NMDA receptors in dopamine neuronsGlycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patternsDeletion of glycine transporter 1 (GlyT1) in forebrain neurons facilitates reversal learning: enhanced cognitive adaptability?ON or OFF?: Modulating the N-Methyl-D-Aspartate Receptor in Major Depression.Development of synaptic transmission to respiratory motoneuronsHuman serine racemase structure/activity relationship studies provide mechanistic insight and point to position 84 as a hot spot for β-elimination function.Modulation of hippocampal synaptic transmission by the kynurenine pathway member xanthurenic acid and other VGLUT inhibitors.Activation of glycine site and GluN2B subunit of NMDA receptors is necessary for ERK/CREB signaling cascade in rostral anterior cingulate cortex in rats: implications for affective pain.GluN2B and GluN2D NMDARs dominate synaptic responses in the adult spinal cordDifferential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.Glycine binding sites of presynaptic NMDA receptors may tonically regulate glutamate release in the rat visual cortex.Glycine transport accounts for the differential role of glycine vs. D-serine at NMDA receptor coagonist sites in the salamander retina.Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice.Dual Ca2+ modulation of glycinergic synaptic currents in rodent hypoglossal motoneurones.Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food.Distinctive glycinergic currents with fast and slow kinetics in thalamus.
P2860
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P2860
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@en
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@nl
type
label
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@en
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@nl
prefLabel
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@en
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@nl
P2860
P1476
Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.
@en
P2093
P2860
P304
P356
10.1152/JN.1998.80.6.3336
P407
P577
1998-12-01T00:00:00Z