about
Physiological characterisation of human iPS-derived dopaminergic neuronsActivation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cellsTransportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response.Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation.Regulation of GATA-2 phosphorylation by mitogen-activated protein kinase and interleukin-3.Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.Efficient, long term production of monocyte-derived macrophages from human pluripotent stem cells under partly-defined and fully-defined conditions.CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells.Differentially expressed, variant U1 snRNAs regulate gene expression in human cellsAssessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infectionDerivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous diseaseER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.The Current State of Naïve Human PluripotencyC9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and FrontotemporalA novel real time imaging platform to quantify macrophage phagocytosisVariant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.Cellular reprogramming: a new approach to modelling Parkinson's disease.The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease.Episomal transgene expression in pluripotent stem cells.Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells.MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons.Excess α-synuclein compromises phagocytosis in iPSC-derived macrophagesAlpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons.Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells.A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells.Stem Cell modeling of Mitochondrial Parkinsonism reveals key functions of OPA1.LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complexNeurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and RafRIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiationSingle-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell PhenotypesThe Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular CardiomyocytesGenome editing in induced pluripotent stem cells rescues TAF1 levels in X-linked dystonia-parkinsonismCellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Sally A Cowley
@es
Sally A Cowley
@nl
Sally A Cowley
@sl
Sally A. Cowley
@en
type
label
Sally A Cowley
@es
Sally A Cowley
@nl
Sally A Cowley
@sl
Sally A. Cowley
@en
altLabel
Sally Anne Cowley
@en
Sally Cowley
@en
prefLabel
Sally A Cowley
@es
Sally A Cowley
@nl
Sally A Cowley
@sl
Sally A. Cowley
@en
P106
P1153
7102482900
P21
P31
P496
0000-0003-0297-6675
P569
2000-01-01T00:00:00Z