Clinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis.
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Understanding the Supersensitive Anti-Drug Antibody Assay: Unexpected High Anti-Drug Antibody Incidence and Its Clinical RelevanceTreatment strategies for multiple sclerosis: When to start, when to change, when to stop?Biomarkers of therapeutic response in multiple sclerosis: current statusAntidrug Antibodies: B Cell Immunity Against TherapyNatalizumab: a review of its use in the management of relapsing-remitting multiple sclerosis.Immunological mechanism of action and clinical profile of disease-modifying treatments in multiple sclerosis.An immunoassay that distinguishes real neuromyelitis optica signals from a labeling detected in patients receiving natalizumabDrug therapy for multiple sclerosis.The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis.Cross-reactive and pre-existing antibodies to therapeutic antibodies--Effects on treatment and immunogenicity.Disrupted balance of T cells under natalizumab treatment in multiple sclerosis.New insights into the pharmacokinetics and pharmacodynamics of natalizumab treatment for patients with multiple sclerosis, obtained from clinical and in vitro studies.Depletion of CD52-positive cells inhibits the development of central nervous system autoimmune disease, but deletes an immune-tolerance promoting CD8 T-cell population. Implications for secondary autoimmunity of alemtuzumab in multiple sclerosis.Long-term safety and efficacy of natalizumab in relapsing-remitting multiple sclerosis: impact on quality of life.Protein-based matrix interferences in ligand-binding assays.Metabolic and safety issues for multiple sclerosis pharmacotherapy--opportunities for personalised medicine.The effect of antidrug antibodies on the sustainable efficacy of biologic therapies in rheumatoid arthritis: practical consequences.Monoclonal antibody therapy in multiple sclerosis: critical appraisal and new perspectives.Body fluid biomarkers for multiple sclerosis--the long road to clinical application.Disease activity return after natalizumab cessation in multiple sclerosis.The majority of natalizumab-treated MS patients have high natalizumab concentrations at time of re-dosing.Integration of metabolomics and proteomics in multiple sclerosis: From biomarkers discovery to personalized medicine.Population Pharmacokinetics and Target Engagement of Natalizumab in Patients With Multiple Sclerosis.Predictors of Response to Multiple Sclerosis Therapeutics in Individual Patients.Blood Biomarkers as Outcome Measures in Inflammatory Neurologic Diseases.Optimization and stratification of multiple sclerosis treatment in fast developing economic countries: a perspective from Qatar.Natalizumab treatment of multiple sclerosis: new insights.Switching natalizumab to fingolimod within 6 weeks reduces recurrence of disease activity in MS patients.Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor.Drug Efficacy Monitoring in Pharmacotherapy of Multiple Sclerosis With Biological AgentsReversibility of the effects of natalizumab on peripheral immune cell dynamics in MS patients.Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases.Soluble interleukin 23 receptor gene therapy with adeno-associated vectors for the treatment of multiple sclerosis.The case for measuring anti-drug antibodies in people with multiple sclerosis.Prediction of natalizumab anti-drug antibodies persistency.Disease activity following pregnancy-related discontinuation of natalizumab in MS.Smokers run increased risk of developing anti-natalizumab antibodies.The chemokine receptor CCR5 Δ32 allele in natalizumab-treated multiple sclerosis.Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab.Identification of Peptide Mimotope Ligands for Natalizumab
P2860
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P2860
Clinical relevance of serum natalizumab concentration and anti-natalizumab antibodies in multiple sclerosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@en
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@nl
type
label
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@en
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@nl
prefLabel
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@en
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@nl
P2093
P2860
P356
P1476
Clinical relevance of serum na ...... ibodies in multiple sclerosis.
@en
P2093
Alexandra Seewann
Anke Vennegoor
Bernard Mj Uitdehaag
Chris H Polman
Eva Mm Strijbis
Gertjan Wolbink
Joep Killestein
Lisanne J Balk
Theo Rispens
P2860
P304
P356
10.1177/1352458512460604
P577
2012-09-19T00:00:00Z