Poor drug distribution as a possible explanation for the results of the PRECISE trial.
about
Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer.The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeuticsBiomarkers for glioma immunotherapy: the next generationMagnetic nanoparticles: an emerging technology for malignant brain tumor imaging and therapyNovel delivery strategies for glioblastomaNovel strategies in glioblastoma surgery aim at safe, supra-maximum resection in conjunction with local therapiesEvolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.Rapid inverse planning for pressure-driven drug infusions in the brainAutomated segmentation tool for brain infusionsInfluence of neuropathology on convection-enhanced delivery in the rat hippocampusIdentification of novel tumor-associated cell surface sialoglycoproteins in human glioblastoma tumors using quantitative proteomicsTherapeutic strategies to improve drug delivery across the blood-brain barrier.Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE studyTime-reversal acoustics and ultrasound-assisted convection-enhanced drug delivery to the brain.Targeted drug delivery across the blood-brain barrier using ultrasound technique.Neurosurgical oncology: advances in operative technologies and adjuncts.Application of iron oxide nanoparticles in glioma imaging and therapy: from bench to bedside.Neural stem cell therapy for cancer.An interleukin 13 receptor α 2-specific peptide homes to human Glioblastoma multiforme xenografts.Imaging of convection enhanced delivery of toxins in humans.Experimental approaches for the treatment of malignant gliomas.Intracranial hyperthermia through local photothermal heating with a fiberoptic microneedle device.Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells.Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastomaFiberoptic microneedle device facilitates volumetric infusate dispersion during convection-enhanced delivery in the brain.Novel platform for MRI-guided convection-enhanced delivery of therapeutics: preclinical validation in nonhuman primate brain.Magnetic resonance imaging properties of convective delivery in diffuse intrinsic pontine gliomas.New agents for targeting of IL-13RA2 expressed in primary human and canine brain tumors.Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance.Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's diseaseEffect of needle insertion speed on tissue injury, stress, and backflow distribution for convection-enhanced delivery in the rat brain.Colocalization of gadolinium-diethylene triamine pentaacetic acid with high-molecular-weight molecules after intracerebral convection-enhanced delivery in humans.Neurocognitive functioning and quality of life in patients with recurrent malignant gliomas treated on a phase Ib trial evaluating topotecan by convection-enhanced deliveryIL-13Rα2-Targeted Therapy Escapees: Biologic and Therapeutic Implications.Predictive models for pressure-driven fluid infusions into brain parenchyma.Targeted toxins for glioblastoma multiforme: pre-clinical studies and clinical implementation.Canine model of convection-enhanced delivery of cetuximab-conjugated iron-oxide nanoparticles monitored with magnetic resonance imaging.Vascular distribution of glioblastoma multiforme at diagnosisDistribution of polymer nanoparticles by convection-enhanced delivery to brain tumors.Pathways of infusate loss during convection-enhanced delivery into the putamen nucleus
P2860
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P2860
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@en
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@nl
type
label
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@en
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@nl
prefLabel
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@en
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@nl
P2093
P50
P1476
Poor drug distribution as a possible explanation for the results of the PRECISE trial.
@en
P2093
Christoph Pedain
David Croteau
Eva Wembacher-Schröder
Gary Archer
James E Herndon
John H Sampson
M Inmaculada Rodríguez-Ponce
Manfred Westphal
Martin L Brady
Michael A Vogelbaum
P304
P356
10.3171/2009.11.JNS091052
P407
P577
2010-08-01T00:00:00Z