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Clinical immunologic approaches for the treatment of Alzheimer's diseaseImmunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.Testing the right target and right drug at the right stageProfile of gantenerumab and its potential in the treatment of Alzheimer's diseaseFunctional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathologyDoes neuroinflammation fan the flame in neurodegenerative diseases?Structural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseCheckpoints to the Brain: Directing Myeloid Cell Migration to the Central Nervous SystemAlzheimer's disease: Targeting the Cholinergic SystemImmunotherapeutic approaches for Alzheimer's diseasePhagocytic clearance in neurodegeneration.Microglia demonstrate age-dependent interaction with amyloid-β fibrilsTransgenic mice overexpressing reticulon 3 develop neuritic abnormalities.Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 miceRobust amyloid clearance in a mouse model of Alzheimer's disease provides novel insights into the mechanism of amyloid-beta immunotherapyReducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates.Inherent anti-amyloidogenic activity of human immunoglobulin gamma heavy chainsEvaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer.DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.Diminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a salmonella-based amyloid-beta derivative vaccine.Neuropathology and amyloid-β spectrum in a bapineuzumab immunotherapy recipient.Value in development of a TAPIR-like mouse monoclonal antibody to Abeta.RTN/Nogo in forming Alzheimer's neuritic plaques.Microglia activation and anti-inflammatory regulation in Alzheimer's diseaseSuppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrowAnimal models of amyloid-beta-related pathologies in Alzheimer's disease.Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studiesAging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapyThe biochemical aftermath of anti-amyloid immunotherapy.Low concentrations of anti-Aβ antibodies generated in Tg2576 mice by DNA epitope vaccine fused with 3C3d molecular adjuvant do not affect AD pathologyCatalytic immunoglobulin gene delivery in a mouse model of Alzheimer's disease: prophylactic and therapeutic applications.Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's diseaseNovel immunological approaches for the treatment of Alzheimer's disease.Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's diseaseMicrotubule-associated protein tau as a therapeutic target in neurodegenerative disease.Prophylaxis and treatment of Alzheimer's disease by delivery of an adeno-associated virus encoding a monoclonal antibody targeting the amyloid Beta protein.Immunotherapy for Alzheimer's disease.Investigating interventions in Alzheimer's disease with computer simulation modelsDetermination of spatial and temporal distribution of microglia by 230nm-high-resolution, high-throughput automated analysis reveals different amyloid plaque populations in an APP/PS1 mouse model of Alzheimer's disease.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Abeta species removal after abeta42 immunization.
@en
Abeta species removal after abeta42 immunization.
@nl
type
label
Abeta species removal after abeta42 immunization.
@en
Abeta species removal after abeta42 immunization.
@nl
prefLabel
Abeta species removal after abeta42 immunization.
@en
Abeta species removal after abeta42 immunization.
@nl
P2093
P1476
Abeta species removal after abeta42 immunization.
@en
P2093
Christina Vlachouli
Clive Holmes
Dale Schenk
David Wilkinson
Dora Games
Edward Barton
Isidro Ferrer
James A R Nicoll
Jim W Neal
Peter Seubert
P304
P356
10.1097/01.JNEN.0000240466.10758.CE
P577
2006-11-01T00:00:00Z