Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development. - Wikidata - awgldk - TriplyDB

Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development.

Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development.

http://www.wikidata.org/entity/Q48417018

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Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis.The Involvement of Neuron-Specific Factors in Dendritic Spinogenesis: Molecular Regulation and Association with Neurological Disorders Alternative splicing of the neurofibromatosis type I pre-mRNA Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome Neurofibromatosis type 1 alternative splicing is a key regulator of Ras signaling in neurons Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein.Neurofibromatosis type 1: modeling CNS dysfunction.Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve.Skin-derived precursor cells as an in vitro modelling tool for the study of type 1 neurofibromatosis Is osseous dysplasia a primary feature of neurofibromatosis 1 (NF1)?Neurofibromatosis type 1: new insights into neurocognitive issues.Genotype-phenotype associations in neurofibromatosis type 1 (NF1): an increased risk of tumor complications in patients with NF1 splice-site mutations?Pendulin, a Drosophila protein with cell cycle-dependent nuclear localization, is required for normal cell proliferation.Gyrification, cortical and subcortical morphometry in neurofibromatosis type 1: an uneven profile of developmental abnormalities Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.Neurofibromatosis type 1 is a disorder of dysplasia: the importance of distinguishing features, consequences, and complications.Links between Schwann cells and melanocytes in development and disease.The NF1 gene in tumor syndromes and melanoma.A mouse embryonic stem cell model of Schwann cell differentiation for studies of the role of neurofibromatosis type 1 in Schwann cell development and tumor formation.Neurofibromatosis type 1: pathology, clinical features and molecular genetics.Loss of neurofibromatosis type I (NF1) gene expression in pheochromocytomas from patients without NF1.Inherited PAX6, NF1 and OTX2 mutations in a child with microphthalmia and aniridia.Specific expression of the neurofibromatosis type 1 gene (NF1) in the hamster Schwann cell.Multivariate pattern analysis reveals subtle brain anomalies relevant to the cognitive phenotype in neurofibromatosis type 1.A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth.NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos.Neurofibromin is actively transported to the nucleus.Neurofibromin C terminus-specific antibody (clone NFC) is a valuable tool for the identification of NF1-inactivated GISTs.Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study.Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.The genetic and neuroanatomical basis of social dysfunction: lessons from neurofibromatosis type 1.Developmental regulation of a neuron-specific neurofibromatosis 1 isoform.Expression of two new protein isoforms of the neurofibromatosis type 1 gene product, neurofibromin, in muscle tissues.

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P2860

Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development.

http://www.wikidata.org/entity/Q48417018

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1992 nî lūn-bûn

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Neurofibromin, a predominantly ...... expressed during development.

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P2860

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes

The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

The neurofibromatosis type 1 gene encodes a protein related to GAP

The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus.

Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients.

cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product.

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10.1002/AJA.1001950307

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